CNTNAP2 抗体 (AA 363-1159)
Quick Overview for CNTNAP2 抗体 (AA 363-1159) (ABIN7601487)
抗原
See all CNTNAP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 363-1159
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原理
- Anti-Caspr2/CNTNAP2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Caspr2/CNTNAP2 Antibody Picoband® (ABIN7601487). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Caspr2/CNTNAP2 recombinant protein (Position: N363-E1159).
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亚型
- IgG
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anti-Contactin Associated Protein-Like 2 (CNTNAP2) (AA 1-1331) antibody
CNTNAP2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Contactin Associated Protein-Like 2 (CNTNAP2) (AA 801-900) antibodyCNTNAP2 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Contactin Associated Protein-Like 2 (CNTNAP2) (AA 1-1331) antibodyCNTNAP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Contactin Associated Protein-Like 2 (CNTNAP2) (AA 1079-1106) antibodyCNTNAP2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB22699 unconjugated
anti-Contactin Associated Protein-Like 2 (CNTNAP2) (Extracellular Domain) antibodyCNTNAP2 适用: 人 WB, IHC, IP, FM 宿主: 小鼠 Monoclonal S67-25 unconjugated
anti-Contactin Associated Protein-Like 2 (CNTNAP2) (AA 1315-1331), (Intracellular) antibodyCNTNAP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Abrahams, B. S., Tentler, D., Perederiy, J. V., Oldham, M. C., Coppola, G., Geschwind, D. H. Genome-wide analyses of human perisylvian cerebral cortical patterning. Proc. Nat. Acad. Sci. 104: 17849-17854, 2007. 2. Alarcon, M., Abrahams, B. S., Stone, J. L., Duvall, J. A., Perederiy, J. V., Bomar, J. M., Sebat, J., Wigler, M., Martin, C. L., Ledbetter, D. H., Nelson, S. F., Cantor, R. M., Geschwind, D. H. Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene. Am. J. Hum. Genet. 82: 150-159, 2008. 3. Arking, D. E., Cutler, D. J., Brune, C. W., Teslovich, T. M., West, K., Ikeda, M., Rea, A., Guy, M., Lin, S., Cook, E. H., Jr., Chakravarti, A. A common genetic variant in the neurexin superfamily member CNTNAP2 increases familial risk of autism. Am. J. Hum. Genet. 82: 160-164, 2008. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))
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别名
- CNTNAP2
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背景
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Synonyms: E3 SUMO-protein ligase PIAS3, Protein inhibitor of activated STAT protein 3, PIAS3
Tissue Specificity: Widely expressed.
Background: Contactin-associated protein-like 2 is a protein that in humans is encoded by the CNTNAP2 gene. This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5 % of chromosome 7 and is one of the largest genes in the human genome. It is ly bound and regulated by forkhead box protein P2, a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and intellectual disability.
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分子量
- 170 kDa
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基因ID
- 26047
抗原
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