RIPOR2 抗体 (AA 362-1020)
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- 抗原 See all RIPOR2 products
- RIPOR2 (rho Family-Interacting Cell Polarization Regulator 2 (RIPOR2))
- 抗原表位
- AA 362-1020
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RIPOR2 antibody is un-conjugated
- 应用范围
- ELISA, Western Blotting (WB), Flow Cytometry (FACS)
- 原理
- Anti-FAM65B/RIPOR2 Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-FAM65B/RIPOR2 Antibody Picoband® (ABIN7601486). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human FAM65B/RIPOR2 recombinant protein (Position: L362-D1020).
- 亚型
- IgG
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anti-rho Family-Interacting Cell Polarization Regulator 2 (RIPOR2) (AA 1-250) antibody
RIPOR2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Dakour, J., Li, H., Morrish, D. W. PL48: a novel gene associated with cytotrophoblast and lineage-specific HL-60 cell differentiation. Gene 185: 153-157, 1997. 2. de Bruijn, S. E., Smits, J. J., Liu, C., Lanting, C. P., Beynon, A. J., Blankevoort, J., Oostrik, J., Koole, W., de Vrieze, E., Cremers, C. W. R. J., Cremers, F. P. M., Roosing, S., Yntema, H. G., Kunst, H. P. M., Zhao, B., Pennings, R. J. E., Kremer, H., DOOFNL Consortium. A RIPOR2 in-frame deletion is a frequent and highly penetrant cause of adult-onset hearing loss. J. Med. Genet. 58: 96-104, 2021. 3. Diaz-Horta, O., Subasioglu-Uzak, A., Grati, M., DeSmidt, A., Foster, J., II, Cao, L., Bademci, G., Tokgoz-Yilmaz, S., Duman, D., Cengiz, F. B., Abad, C., Mittal, R., Blanton, S., Liu, X. Z., Farooq, A., Walz, K., Lu, Z., Tekin, M. FAM65B is a membrane-associated protein of hair cell stereocilia required for hearing. Proc. Nat. Acad. Sci. 111: 9864-9868, 2014. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- RIPOR2 (rho Family-Interacting Cell Polarization Regulator 2 (RIPOR2))
- 别名
- RIPOR2 (RIPOR2 产品)
- 背景
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Synonyms: Protein Bop, BH3-only protein, Retrotransposon Gag-like protein 10, RTL10, BOP, C22orf29
Tissue Specificity: Ubiquitously expressed.
Background: RHO family interacting cell polarization regulator 2 is a protein that in humans is encoded by the RIPOR2 gene. This gene encodes an atypical inhibitor of the small G protein RhoA. Inhibition of RhoA activity by the encoded protein mediates myoblast fusion and polarization of T cells and neutrophils. The encoded protein is a component of hair cell stereocilia that is essential for hearing. A splice site mutation in this gene results in hearing loss in human patients.
- 分子量
- 120 kDa
- 基因ID
- 9750
- UniProt
- Q9Y4F9
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