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CRH 抗体 (AA 185-196)

Name: CRH 抗体 (AA 185-196)
SKU: ABIN726800
Availability: OutOfStock

This anti-CRH antibody is a 兔多克隆 antibody detecting CRH in WB, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 大鼠和小鼠. This Primary Antibody has been cited in 2+ publications.

The alcohol-preferring (P) rats have a higher percentage of ventral tegmental area (VTA) TH+ neurons that co-express Toll-like receptor 4 (TLR4) and the γ-aminobutyric acidA receptor (GABAAR) α2 subunit (α2) than alcohol-non-preferring (NP) rats. (CRH 抗体 (AA 185-196))

1 image

(2 references)

产品编号 ABIN726800

发货至: 中国

Datasheet as PDF

Quick Overview for CRH 抗体 (AA 185-196) (ABIN726800)

抗原

See all CRH 抗体

CRH (Corticotropin Releasing Hormone (CRH))

适用

人, 大鼠, 小鼠

宿主

兔

克隆类型

多克隆

标记

This CRH antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product CRH Primary Antibody

抗原表位
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AA 185-196

交叉反应

人, 小鼠, 大鼠

预测反应

Dog,Pig,Chicken,Rabbit,Guinea Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human CRF

亚型

IgG
anti-Corticotropin Releasing Hormone (CRH) (AA 40-195) antibody
CRH 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Corticotropin Releasing Hormone (CRH) (AA 154-196) antibody
CRH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated

anti-Corticotropin Releasing Hormone (CRH) (N-Term) antibody
CRH 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Corticotropin Releasing Hormone (CRH) (AA 39-187) antibody
CRH 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Corticotropin Releasing Hormone (CRH) antibody
Microarray verified CRH 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB701026 unconjugated

anti-Corticotropin Releasing Hormone (CRH) antibody
Microarray verified CRH 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB189288 unconjugated

anti-Corticotropin Releasing Hormone (CRH) antibody
Microarray verified CRH 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB561789 unconjugated

anti-Corticotropin Releasing Hormone (CRH) (AA 25-194) antibody
CRH 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Corticotropin Releasing Hormone (CRH) (AA 29-45) antibody
CRH 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Corticotropin Releasing Hormone (CRH) (AA 28-160) antibody
CRH 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Balan, Warnock, Puche, Gondre-Lewis, June, Aurelian: "The GABAA Receptor α2 Subunit Activates a Neuronal TLR4 Signal in the Ventral Tegmental Area that Regulates Alcohol and Nicotine Abuse." in: Brain sciences, Vol. 8, Issue 4, (2018) (PubMed).

Balan, Warnock, Puche, Gondre-Lewis, Aurelian: "Innately activated TLR4 signal in the nucleus accumbens is sustained by CRF amplification loop and regulates impulsivity." in: Brain, behavior, and immunity, (2017) (PubMed).
抗原

CRH (Corticotropin Releasing Hormone (CRH))

别名

CRF

背景

Synonyms: Corticoliberin, Corticoliberin precursor, Corticotropin releasing factor, Corticotropin releasing hormone, Corticotropin releasing hormone deficiency included, crf, crh, crh deficiency included, corticoliberin preproprotein, CRF_HUMAN, Corticotropin-releasing factor, CRF, CRH, Corticotropin-releasing hormone.
Background: Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010].

基因ID

1392

UniProt

P06850

途径

Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Feeding Behaviour