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OAS2 抗体 (AA 35-742)

This anti-OAS2 antibody is a 兔 多克隆 antibody detecting OAS2 in WB, ELISA 和 FACS. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7601436
发货至: 中国

Quick Overview for OAS2 抗体 (AA 35-742) (ABIN7601436)

抗原

See all OAS2 抗体
OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))

适用

  • 38
  • 10
  • 4
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  • 3
  • 2
  • 2
  • 2
  • 1
小鼠, 大鼠

宿主

  • 26
  • 11
  • 2

克隆类型

  • 28
  • 11
多克隆

标记

  • 27
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This OAS2 antibody is un-conjugated

应用范围

  • 26
  • 17
  • 14
  • 6
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 7
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 35-742

    原理

    Anti-OAS2 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-OAS2 Antibody Picoband® (ABIN7601436). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse OAS2 recombinant protein (Position: H35-K742). Mouse OAS2 shares 62.4% and 77.5% amino acid (aa) sequence identity with human and rat ATF5, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
    ELISA, 0.1-0.5 μg/mL, Mouse
    1. Hovanessian, A. G., Laurent, A. G., Chebath, J., Galabru, J., Robert, N., Svab, J. Identification of 69-kd and 100-kd forms of 2-5A synthetase in interferon-treated human cells by specific monoclonal antibodies. EMBO J. 6: 1273-1280, 1987. 2. Hovnanian, A., Rebouillat, D., Mattei, M.-G., Levy, E. R., Marie, I., Monaco, A. P., Hovanessian, A. G. The human 2-prime,5-prime-oligoadenylate synthetase locus is composed of three distinct genes clustered on chromosome 12q24.2 encoding the 100-, 69-, and 40- kDa forms. Genomics 52: 267-277, 1998. 3. Marie, I., Galabru, J., Svab, J., Hovanessian, A. G. Preparation and characterization of polyclonal antibodies specific for the 69 and 100 k-dalton forms of human 2-5A synthetase. Biochem. Biophys. Res. Commun. 160: 580-587, 1989.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))

    别名

    OAS2

    背景

    Synonyms: Oas2, oasl11, 2'-5'-oligoadenylate synthase 2, (2-5'oligo(A synthase 2, 2-5A synthase 2, EC 2.7.7.84, 2',5'-oligoadenylate synthetase-like 11

    Background: 2'-5'-oligoadenylate synthetase 2 is an enzyme that in humans is encoded by the OAS2 gene. Enables 2'-5'-oligoadenylate synthetase activity and double-stranded RNA binding activity. Involved in defense response to virus, regulation of lactation, and type I interferon signaling pathway. Acts upstream of or within RNA catabolic process, interleukin-27-mediated signaling pathway, and response to bacterium. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytosol, membrane, and nucleoplasm. Is expressed in embryo. Orthologous to human OAS2 (2'-5'-oligoadenylate synthetase 2).

    分子量

    69 kDa

    基因ID

    246728

    UniProt

    E9Q9A9

    途径

    Hepatitis C
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