Scinderin 抗体 (AA 35-617)
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- 抗原 See all Scinderin (SCIN) 抗体
- Scinderin (SCIN)
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抗原表位
- AA 35-617
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Scinderin antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Anti-SCIN Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-SCIN Antibody Picoband® (ABIN7601434). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human SCIN recombinant protein (Position: S35-Y617).
- 亚型
- IgG
- Top Product
- Discover our top product SCIN Primary Antibody
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anti-Scinderin (SCIN) (AA 1-468) antibody
SCIN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Scinderin (SCIN) (AA 1-468) antibodySCIN 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Scinderin (SCIN) (AA 556-703) antibodySCIN 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Scinderin (SCIN) antibodySCIN 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Ehre, C., Rossi, A. H., Abdullah, L. H., De Pestel, K., Hill, S., Olsen, J. C., Davis, C. W. Barrier role of actin filaments in regulated mucin secretion from airway goblet cells. Am. J. Physiol. Cell Physiol. 288: C46-C56, 2005. 2. Gross, M. B. Personal Communication. Baltimore, Md. 5/20/2010. 3. Nagase, T., Kikuno, R., Ohara, O. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. DNA Res. 8: 179-187, 2001. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- Scinderin (SCIN)
- 别名
- SCIN (SCIN 产品)
- 背景
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Synonyms: BAG family molecular chaperone regulator 5,BAG-5,Bcl-2-associated athanogene 5,BAG5,KIAA0873,
Tissue Specificity: Expressed in all tissues examined with lower levels in brain and testis.
Background: Scinderin (also known as adseverin) is a protein that in humans is encoded by the SCIN gene. Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes (By similarity).
- 分子量
- 80 kDa
- 基因ID
- 85477
- UniProt
- Q9Y6U3
- 途径
- Regulation of Actin Filament Polymerization
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