LGI1 抗体 (AA 35-557)
Quick Overview for LGI1 抗体 (AA 35-557) (ABIN7601430)
抗原
See all LGI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 35-557
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原理
- Anti-Lgi1/EPT/LGI1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Lgi1/EPT/LGI1 Antibody Picoband® (ABIN7601430). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Lgi1/EPT/LGI1 recombinant protein (Position: K35-A557).
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亚型
- IgG
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anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 451-557) antibody
LGI1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibodyLGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 unconjugated
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibody (HRP)LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 HRP
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibody (FITC)LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 FITC
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibody (Biotin)LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 Biotin
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibody (PE)LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 PE
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibody (PerCP)LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 PerCP
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibody (APC)LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 APC
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibody (Atto 488)LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 Atto 488
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibody (Atto 594)LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 Atto 594
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Anderson, M. P. Arrested glutamatergic synapse development in human partial epilepsy. Epilepsy Curr. 10: 153-158, 2010. 2. Bigner, S. H., Vogelstein, B. Cytogenetics and molecular genetics of malignant gliomas and medulloblastoma. Brain Path. 1: 12-18, 1990. 3. Bisulli, F., Tinuper, P., Scudellaro, E., Naldi, I., Bagattin, A., Avoni, P., Michelucci, R., Nobile, C. A de novo LGI1 mutation in sporadic partial epilepsy with auditory features. Ann. Neurol. 56: 455-456, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))
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别名
- LGI1
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背景
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Synonyms: Complement component C7, C7
Tissue Specificity: Widely expressed.
Background: Leucine-rich, glioma inactivated 1, also known as LGI1, is a protein which in humans is encoded by the LGI1 gene. This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.
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分子量
- 64 kDa
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基因ID
- 9211
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UniProt
- O95970
抗原
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