OXCT1 抗体 (AA 35-309)
Quick Overview for OXCT1 抗体 (AA 35-309) (ABIN7601419)
抗原
See all OXCT1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 35-309
-
原理
- Anti-OXCT1/SCOT Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-OXCT1/SCOT Antibody Picoband® (ABIN7601419). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human OXCT1/SCOT recombinant protein (Position: S35-A309).
-
亚型
- IgG
-
-
anti-3-Oxoacid CoA Transferase 1 (OXCT1) (AA 40-489) antibody
OXCT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-3-Oxoacid CoA Transferase 1 (OXCT1) (AA 1-520) antibodyOXCT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-3-Oxoacid CoA Transferase 1 (OXCT1) (Internal Region) antibodyOXCT1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-3-Oxoacid CoA Transferase 1 (OXCT1) (AA 261-520) antibodyOXCT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-3-Oxoacid CoA Transferase 1 (OXCT1) (AA 40-520) antibodyOXCT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-3-Oxoacid CoA Transferase 1 (OXCT1) (AA 1-520) antibodyOXCT1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-3-Oxoacid CoA Transferase 1 (OXCT1) (Middle Region) antibodyOXCT1 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 斑马鱼, 犬, 马, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-3-Oxoacid CoA Transferase 1 (OXCT1) antibodyOXCT1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-3-Oxoacid CoA Transferase 1 (OXCT1) (AA 272-306) antibodyOXCT1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB50059 unconjugated
anti-3-Oxoacid CoA Transferase 1 (OXCT1) (AA 261-520) antibodyOXCT1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat, Monkey
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fukao, T., Mitchell, G. A., Song, X.-Q., Nakamura, H., Kassovska-Bratinova, S., Orii, K. E., Wraith, J. E., Besley, G., Wanders, R. J. A., Niezen-Koning, K. E., Berry, G. T., Palmieri, M., Kondo, N. Succinyl-CoA:3-ketoacid CoA transferase (SCOT): cloning of the human SCOT gene, tertiary structural modeling of the human SCOT monomer, and characterization of three pathogenic mutations. Genomics 68: 144-151, 2000. 2. Hori, T., Fukao, T., Murase, K., Sakaguchi, N., Harding, C. O., Kondo, N. Molecular basis of two-exon skipping (exons 12 and 13) by c.1248+5g-a in OXCT1 gene: study on intermediates of OXCT1 transcripts in fibroblasts. Hum. Mutat. 34: 473-480, 2013. 3. Kassovska-Bratinova, S., Fukao, T., Song, X.-Q., Duncan, A. M. V., Chen, H. S., Robert, M.-F., Perez-Cerda, C., Ugarte, M., Chartrand, C., Vobecky, S., Kondo, N., Mitchell, G. A. Succinyl CoA:3-oxoacid CoA transferase (SCOT): human cDNA cloning, human chromosomal mapping to 5p13, and mutation detection in a SCOT-deficient patient. Am. J. Hum. Genet. 59: 519-528, 1996. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- OXCT1 (3-Oxoacid CoA Transferase 1 (OXCT1))
-
别名
- OXCT1
-
背景
-
Synonyms: DNA- (apurinic or apyrimidinic site) lyase 2,3.1.-.-,4.2.99.18,AP endonuclease XTH2,APEX nuclease 2,APEX nuclease-like 2,Apurinic-apyrimidinic endonuclease 2,AP endonuclease 2,APEX2,APE2, APEXL2, XTH2,
Tissue Specificity: Highly expressed in brain and kidney. Weakly expressed in the fetal brain. .
Background: 3-oxoacid CoA-transferase 1 (OXCT1) is an enzyme that in humans is encoded by the OXCT1 gene. It is also known as succinyl-CoA-3-oxaloacid CoA transferase (SCOT). This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.
-
分子量
- 56 kDa
-
基因ID
- 5019
-
UniProt
- P55809
-
途径
- Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
抗原
-
