ENPP1 抗体 (AA 347-789)
Quick Overview for ENPP1 抗体 (AA 347-789) (ABIN7601410)
抗原
See all ENPP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 347-789
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原理
- Anti-ENPP1/PC1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ENPP1/PC1 Antibody Picoband® (ABIN7601410). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ENPP1/PC1 recombinant protein (Position: E347-N789).
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亚型
- IgG
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anti-Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1) (C-Term) antibody
Verified ENPP1 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1) antibodyKO Validated ENPP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1) (AA 568-793) antibodyENPP1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1) (AA 6-34), (N-Term) antibodyENPP1 适用: 人 WB 宿主: 兔 Polyclonal RB41733 unconjugated
anti-Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1) (AA 1-873) antibodyENPP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1) (AA 251-350) antibodyENPP1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1) (AA 41-140) antibodyENPP1 适用: 小鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1) (AA 362-518) antibodyENPP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1) (AA 1-75) antibodyENPP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1) (AA 29-57), (N-Term) antibodyENPP1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB30657 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 1-2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Abate, N., Carulli, L., Cabo-Chan, Jr., A., Chandalia, M., Snell, P. G., Grundy, S. M. Genetic polymorphism PC-1 K121Q and ethnic susceptibility to insulin resistance. J. Clin. Endocr. Metab. 88: 5927-5934, 2003. 2. Bottcher, Y., Korner, A., Reinehr, T., Enigk, B., Kiess, W., Stumvoll, M., Kovacs, P. ENPP1 variants and haplotypes predispose to early onset obesity and impaired glucose and insulin metabolism in German obese children. J. Clin. Endocr. Metab. 91: 4948-4952, 2006. 3. Buckley, M. F., Goding, J. W. Plasma cell membrane glycoprotein gene Pca-1 (alkaline phosphodiesterase I) is linked to the proto-oncogene Myb on mouse chromosome 10. Immunogenetics 36: 199-201, 1992. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))
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别名
- ENPP1
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背景
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Synonyms: Metabotropic glutamate receptor 5, mGluR5, GRM5, GPRC1E, MGLUR5
Tissue Specificity: Isoform 1 and isoform 2 are detected in bone marrow cells, spermatogonia and spermatocytes, but not in round spermatids, elongating spermatids and spermatozoa. Isoform 3 is detected in round spermatids, elongating spermatids and spermatozoa, but not in spermatogonia and spermatocytes (at protein level). Isoform 1 is widely expressed and detected in fetal liver and bone marrow. Isoform 3 is detected in bone marrow cells enriched in hematopoietic stem cells.
Background: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (PC-1, CD203a) is an enzyme that in humans is encoded by the ENPP1 gene. This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.
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分子量
- 130-150 kDa
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基因ID
- 5167
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UniProt
- P22413
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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