DAZL 抗体 (AA 34-281)
Quick Overview for DAZL 抗体 (AA 34-281) (ABIN7601384)
抗原
See all DAZL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 34-281
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原理
- Anti-DAZL Picoband® Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-DAZL Picoband® Antibody (ABIN7601384). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DAZL recombinant protein (Position: E34-R281).
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亚型
- IgG
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anti-Deleted in Azoospermia-Like (DAZL) (AA 186-295) antibody
DAZL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Azoospermia-Like (DAZL) (Internal Region) antibodyVerified DAZL 适用: 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Deleted in Azoospermia-Like (DAZL) (AA 130-250) antibodyDAZL 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Azoospermia-Like (DAZL) (AA 1-295) antibodyDAZL 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Deleted in Azoospermia-Like (DAZL) (AA 218-267) antibodyDAZL 适用: 人, 小鼠, 大鼠, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Azoospermia-Like (DAZL) (C-Term) antibodyDAZL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Azoospermia-Like (DAZL) (C-Term) antibodyDAZL 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Bartoloni, L., Cazzadore, C., Ferlin, A., Garolla, A., Foresta, C. Lack of the T54A polymorphism of the DAZL gene in infertile Italian patients. Molec. Hum. Reprod. 10: 613-615, 2004. 2. Eberhart, C. G., Maines, J. Z., Wasserman, S. A. Meiotic cell cycle requirement for a fly homologue of human Deleted in Azoospermia. Nature 381: 783-785, 1996. 3. Kee, K., Angeles, V. T., Flores, M., Nguyen, H. N., Reijo Pera, R. A. Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation. Nature 462: 222-225, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- DAZL (Deleted in Azoospermia-Like (DAZL))
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别名
- DAZL
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背景
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Synonyms: Deleted in azoospermia-like, DAZ homolog, DAZ-like autosomal, Deleted in azoospermia-like 1, SPGY-like-autosomal, DAZL, DAZH, DAZL1, DAZLA, SPGYLA
Background: Deleted in azoospermia-like is a protein that in humans is encoded by the DAZL gene. It is mapped to 3p24.3. The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 38 kDa
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基因ID
- 1618
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UniProt
- Q92904
抗原
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