SIM2 抗体 (AA 337-609)
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Quick Overview for SIM2 抗体 (AA 337-609) (ABIN7601370)
抗原
See all SIM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 337-609
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原理
- Anti-SIM2 Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human SIM2 shares 85.8% amino acid (aa) sequence identity with mouse SIM2.
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产品特性
- Anti-SIM2 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Monkey, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SIM2 recombinant protein (Position: Y337-R609). Human SIM2 shares 85.8% amino acid (aa) sequence identity with mouse SIM2.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Monkey, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- SIM2 (Single-Minded Homolog 2 (SIM2))
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别名
- SIM2
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背景
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Background: Single-minded homolog 2 is a protein that in humans is encoded by the SIM2 gene. This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Gene Full Name: SIM bHLH transcription factor 2
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分子量
- 65 kDa
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基因ID
- 6493
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UniProt
- Q14190
抗原
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