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CLPX 抗体 (AA 337-574)

This anti-CLPX antibody is a 小鼠 单克隆 antibody detecting CLPX in WB, IF 和 ICC. Suitable for 人.
产品编号 ABIN7601368
发货至: 中国

Quick Overview for CLPX 抗体 (AA 337-574) (ABIN7601368)

抗原

See all CLPX 抗体
CLPX (ClpX Caseinolytic Peptidase X (CLPX))

适用

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宿主

  • 29
小鼠

克隆类型

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单克隆

标记

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This CLPX antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

11C11
  • 抗原表位

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    AA 337-574

    原理

    Anti-CLPX Antibody Picoband® (monoclonal, 11C11)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-CLPX Antibody Picoband® (monoclonal, 11C11) (ABIN7601368). Tested in IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    免疫原

    E. coli-derived human CLPX recombinant protein (Position: A337-E574).

    亚型

    IgG2b
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    1. Corydon, T. J., Wilsbech, M., Jespersgaard, C., Andresen, B. S., Borglum, A. D., Pedersen, S., Bolund, L., Gregersen, N., Bross, P. Human and mouse mitochondrial orthologs of bacterialClpX. Mammalian Genome 11: 899-905, 2000. 2. Kang, S. G., Dimitrova, M. N., Ortega, J., Ginsburg, A., Maurizi, M. R. Human mitochondrial ClpP is a stable heptamer that assembles into a tetradecamer in the presence of ClpX. J. Biol. Chem. 280: 35424-35432, 2005.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    CLPX (ClpX Caseinolytic Peptidase X (CLPX))

    别名

    CLPX

    背景

    Synonyms: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial, CLPX

    Tissue Specificity: Higher expression in skeletal muscle and heart and to a lesser extent in liver, brain, placenta, lung, kidney and pancreas.

    Background: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial is an enzyme that in humans is encoded by the CLPX gene. This protein is a member of the family of AAA Proteins (AAA+ ATPase) and is to form the protein complex of Clp protease. The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.

    分子量

    69 kDa

    基因ID

    10845

    UniProt

    O76031
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