CCR7 抗体 (AA 332-371)
Quick Overview for CCR7 抗体 (AA 332-371) (ABIN7601362)
抗原
See all CCR7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 332-371
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原理
- Anti-CCR7 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CCR7 Antibody Picoband® (ABIN7601362). Tested in ELISA, Flow Cytometry, IHC applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CCR7 recombinant protein (Position: K332-E371).
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亚型
- IgG
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anti-Chemokine (C-C Motif) Receptor 7 (CCR7) (AA 25-59) antibody
CCR7 适用: 人, 小鼠, 大鼠, 绵羊 FACS, WB, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) antibodyCCR7 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 4B7B8 unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) (AA 11-37), (N-Term) antibodyCCR7 适用: 人, 小鼠 FACS, WB, IF, IHC (p) 宿主: 兔 Polyclonal RB21736 unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) antibodyCCR7 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) (AA 11-37) antibodyCCR7 适用: 人, 小鼠 FACS, WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) (AA 1-100) antibodyCCR7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) (AA 332-378) antibodyCCR7 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) (C-Term) antibodyCCR7 适用: 人, 猴, Cow, Bat, 马 IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) (C-Term) antibodyCCR7 适用: 人, 猴, Cow IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) antibody (APC)CCR7 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 4B12 APC
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应用备注
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Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Beauvillain, C., Cunin, P., Doni, A., Scotet, M., Jaillon, S., Loiry, M.-L., Magistrelli, G., Masternak, K., Chevailler, A., Delneste, Y., Jeannin, P. CCR7 is involved in the migration of neutrophils to lymph nodes. Blood 117: 1196-1204, 2011. 2. Birkenbach, M., Josefsen, K., Yalamanchili, R., Lenoir, G., Kieff, E. Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors. J. Virol. 67: 2209-2220, 1993. 3. Buonamici, S., Trimarchi, T., Ruocco, M. G., Reavie, L., Cathelin, S., Mar, B. G., Klinakis, A., Lukyanov, Y., Tseng, J.-C., Sen, F., Gehrie, E., Li, M., and 10 others. CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia. Nature 459: 1000-1004, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
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别名
- CCR7
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背景
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Synonyms: DNA excision repair protein ERCC-1, ERCC1
Tissue Specificity: Expressed in fetal brain.
Background: C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.
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分子量
- 38 kDa
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基因ID
- 1236
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UniProt
- P32248
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途径
- Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
抗原
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