IFNAR2 抗体 (AA 33-466)
Quick Overview for IFNAR2 抗体 (AA 33-466) (ABIN7601353)
抗原
See all IFNAR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 33-466
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原理
- Anti-IFNAR2 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-IFNAR2 Antibody Picoband® (ABIN7601353). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human IFNAR2 recombinant protein (Position: D33-Q466).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Croze, E., Russell-Harde, D., Wagner, T. C., Pu, H., Pfeffer, L. M., Perez, H. D. The human type I interferon receptor: identification of the interferon beta-specific receptor-associated phosphoprotein. J. Biol. Chem. 271: 33165-33168, 1996. 2. Croze, E., Usacheva, A., Asarnow, D., Minshall, R.D., Perez, H.D., Colamonici, O. Receptor for activated C-kinase (RACK-1), a WD motif-containing protein, specifically associates with the human type I IFN receptor. J. Immun. 165: 5127-5132, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
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别名
- IFNAR2
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背景
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Synonyms: Interferon alpha/beta receptor 2, IFN-R-2, IFN-alpha binding protein, IFN-alpha/beta receptor 2, Interferon alpha binding protein, Type I interferon receptor 2, IFNAR2, IFNABR, IFNARB
Tissue Specificity: Isoform 3 is detected in the urine. Expressed in blood cells. Expressed in lymphoblastoid and fibrosarcoma cell lines.
Background: Interferon-alpha/beta receptor beta chain is a protein that in humans is encoded by the IFNAR2 gene. It is mapped to 21q22.11. The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.
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分子量
- 65 kDa
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基因ID
- 3455
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UniProt
- P48551
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途径
- JAK/STAT Signaling, Hepatitis C
抗原
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