ANTXR1 抗体 (AA 33-301)
Quick Overview for ANTXR1 抗体 (AA 33-301) (ABIN7601347)
抗原
See all ANTXR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 33-301
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原理
- Anti-TEM8/ATR/ANTXR1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TEM8/ATR/ANTXR1 Antibody Picoband® (ABIN7601347). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TEM8/ATR/ANTXR1 recombinant protein (Position: E33-D301).
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亚型
- IgG
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anti-anthrax Toxin Receptor 1 (ANTXR1) (C-Term) antibody
Verified ANTXR1 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (Internal Region) antibodyANTXR1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (AA 315-564) antibodyANTXR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (AA 481-497) antibodyANTXR1 适用: 人, 犬, 兔, 猴 WB 宿主: 小鼠 Monoclonal 200C1339(SB20) unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (AA 396-445) antibodyANTXR1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 猴, Bat, 小鸡, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (C-Term) antibodyANTXR1 适用: 人, 小鼠, 大鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (AA 358-386) antibodyANTXR1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15324 unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (C-Term) antibodyANTXR1 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (Intermediate Domain) antibodyANTXR1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (AA 365-394), (Tyr382) antibodyANTXR1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Baxova, A., Kozlowski, K., Obersztyn, E., Zeman, J. GAPO syndrome (radiographic clues to early diagnosis). Radiol. Med. 93: 289-291, 1997. 2. Bayram, Y., Pehlivan, D., Karaca, E., Gambin, T., Jhangiani, S. N., Erdin, S., Gonzaga-Jauregui, C., Wiszniewski, W., Muzny, D., Baylor-Hopkins Center for Mendelian Genomics, Elcioglu, N. H., Yildirim, M. S., Bozkurt, B., Zamani, A. G., Boerwinkle, E., Gibbs, R. A., Lupski, J. R.. Whole exome sequencing identifies three novel mutations in ANTXR1 in families with GAPO syndrome. Am. J. Med. Genet. 164A: 2328-2334, 2014. 3. Besschetnova, T. Y., Ichimura, T., Katebi, N., St. Croix, B., Bonventre, J. V., Olsen, B. R. Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis. Matrix Biol. 42: 56-73, 2015. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
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别名
- ANTXR1
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背景
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Synonyms: Voltage-dependent calcium channel subunit alpha-2/delta-2, Voltage-gated calcium channel subunit alpha-2/delta-2, Voltage-dependent calcium channel subunit alpha-2-2, Voltage-dependent calcium channel subunit delta-2, CACNA2D2, KIAA0558
Tissue Specificity: Predominantly present in cerebellar cortex. Present in various lung tumor cell lines, while it is absent in normal lung (at protein level). Highly expressed in heart, lung, testis, pancreas and skeletal muscle. Also expressed in kidney, liver, placenta and brain.
Background: Anthrax toxin receptor 1 (ANTXR1 or also known asTEM8) is a protein that in humans is encoded by the ANTXR1 gene. This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
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分子量
- 80 kDa
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基因ID
- 84168
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UniProt
- Q9H6X2
抗原
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