PITRM1 抗体 (AA 33-1037)
Quick Overview for PITRM1 抗体 (AA 33-1037) (ABIN7601336)
抗原
See all PITRM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 33-1037
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原理
- Anti-PITRM1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PITRM1 Antibody Picoband® (ABIN7601336). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PITRM1 recombinant protein (Position: A33-K1037).
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亚型
- IgG
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anti-Pitrilysin Metallopeptidase 1 (PITRM1) (AA 758-1037) antibody
PITRM1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pitrilysin Metallopeptidase 1 (PITRM1) antibodyPITRM1 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pitrilysin Metallopeptidase 1 (PITRM1) (AA 1-534) antibodyPITRM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H3 unconjugated
anti-Pitrilysin Metallopeptidase 1 (PITRM1) (AA 758-1037) antibodyPITRM1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Pitrilysin Metallopeptidase 1 (PITRM1) (AA 653-926) antibodyPITRM1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pitrilysin Metallopeptidase 1 (PITRM1) (AA 544-806) antibodyPITRM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Falkevall, A., Alikhani, N., Bhushan, S., Pavlov, P. F., Busch, K., Johnson, K. A., Eneqvist, T., Tjernberg, L., Ankarcrona, M., Glaser, E. Degradation of the amyloid beta-protein by the novel mitochondrial peptidasome, PreP. J. Biol. Chem. 281: 29096-29104, 2006. 2. Mzhavia, N., Berman, Y. L., Qian, Y., Yan, L., Devi, L. A. Cloning, expression, and characterization of human metalloprotease 1: a novel member of the pitrilysin family of metalloendoproteases. DNA Cell Biol. 18: 369-380, 1999. 3. Teixeira, P. F., Pinho, C. M., Branca, R. M., Lehtio, J., Levine, R. L., Glaser, E. In vitro oxidative inactivation of human presequence protease (hPreP). Free Radic. Biol. Med. 53: 2188-2195, 2012. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))
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别名
- PITRM1
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背景
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Synonyms: Immunoglobulin lambda-like polypeptide 1, CD179 antigen-like family member B, Ig lambda-5, Immunoglobulin omega polypeptide, Immunoglobulin-related protein 14.1, CD179b, IGLL1, IGL1
Tissue Specificity: Expressed only in pre-B-cells and a special B-cell line (which is surface Ig negative).
Background: Pitrilysin metallopeptidase 1 also known as presequence protease, mitochondrial (PreP) and metalloprotease 1 (MTP-1) is an enzyme that in humans is encoded by the PITRM1 gene. The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease.
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分子量
- 117 kDa
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基因ID
- 10531
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途径
- PI3K-Akt Signaling, SARS-CoV-2 Protein Interactome
抗原
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