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FAM111B 抗体 (AA 328-726)

This anti-FAM111B antibody is a 兔 多克隆 antibody detecting FAM111B in ELISA, IHC, WB 和 FACS. Suitable for 人.
产品编号 ABIN7601335
发货至: 中国

Quick Overview for FAM111B 抗体 (AA 328-726) (ABIN7601335)

抗原

FAM111B (Family with Sequence Similarity 111, Member B (FAM111B))

适用

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宿主

  • 15

克隆类型

  • 15
多克隆

标记

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This FAM111B antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

    • 2
    • 1
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    AA 328-726

    原理

    Anti-FAM111B Antibody Picoband®

    产品特性

    Anti-FB Antibody Picoband® (ABIN7601335). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human FAM111B recombinant protein (Position: Q328-D726). Human FAM111B shares 45.4% amino acid (aa) sequence identity with mouse FAM111B.
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry, 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Khumalo, N. P., Pillay, K., Beighton, P., Wainwright, H., Walker, B., Saxe, N., Mayosi, B. M., Bateman, E. D. Poikiloderma, tendon contracture and pulmonary fibrosis: a new autosomal dominant syndrome? Brit. J. Derm. 155: 1057-1061, 2006. 2. Mercier, S., Kury, S., Shaboodien, G., Houniet, D. T., Khumalo, N. P., Bou-Hanna, C., Bodak, N., Cormier-Daire, V., David, A., Faivre, L., Figarella-Branger, D., Gherardi, R. K., and 18 others. Mutations in FAM111B cause hereditary fibrosing poikiloderma with tendon contracture, myopathy, and pulmonary fibrosis. Am. J. Hum. Genet. 93: 1100-1107, 2013.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    FAM111B (Family with Sequence Similarity 111, Member B (FAM111B))

    别名

    FAM111B

    背景

    This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐,like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1.

    分子量

    85 kDa

    基因ID

    374393
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