FAM111B 抗体 (AA 328-726)
FAM111B
适用: 人
ELISA, IHC, WB, FACS
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all FAM111B products
- FAM111B (Family with Sequence Similarity 111, Member B (FAM111B))
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抗原表位
- AA 328-726
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FAM111B antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS)
- 原理
- Anti-FAM111B Antibody Picoband®
- 产品特性
- Anti-FB Antibody Picoband® (ABIN7601335). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human FAM111B recombinant protein (Position: Q328-D726). Human FAM111B shares 45.4% amino acid (aa) sequence identity with mouse FAM111B.
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anti-Family with Sequence Similarity 111, Member B (FAM111B) antibody
FAM111B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 111, Member B (FAM111B) (C-Term) antibodyFAM111B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Khumalo, N. P., Pillay, K., Beighton, P., Wainwright, H., Walker, B., Saxe, N., Mayosi, B. M., Bateman, E. D. Poikiloderma, tendon contracture and pulmonary fibrosis: a new autosomal dominant syndrome? Brit. J. Derm. 155: 1057-1061, 2006. 2. Mercier, S., Kury, S., Shaboodien, G., Houniet, D. T., Khumalo, N. P., Bou-Hanna, C., Bodak, N., Cormier-Daire, V., David, A., Faivre, L., Figarella-Branger, D., Gherardi, R. K., and 18 others. Mutations in FAM111B cause hereditary fibrosing poikiloderma with tendon contracture, myopathy, and pulmonary fibrosis. Am. J. Hum. Genet. 93: 1100-1107, 2013. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- FAM111B (Family with Sequence Similarity 111, Member B (FAM111B))
- 别名
- FAM111B (FAM111B 产品)
- 背景
- This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐,like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1.
- 分子量
- 85 kDa
- 基因ID
- 374393
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