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YTHDC1 抗体 (AA 326-651)

This anti-YTHDC1 antibody is a 兔 多克隆 antibody detecting YTHDC1 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7601331
发货至: 中国

Quick Overview for YTHDC1 抗体 (AA 326-651) (ABIN7601331)

抗原

See all YTHDC1 抗体
YTHDC1 (YTH Domain Containing 1 (YTHDC1))

适用

  • 15
  • 7
  • 6
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 15

克隆类型

  • 15
多克隆

标记

  • 11
  • 2
  • 1
  • 1
This YTHDC1 antibody is un-conjugated

应用范围

  • 10
  • 7
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 7
    • 1
    • 1
    • 1
    • 1
    AA 326-651

    原理

    Anti-YTHDC1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-YTHDC1 Antibody Picoband® (ABIN7601331). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human YTHDC1 recombinant protein (Position: S326-K651).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Hartmann, A. M., Nayler, O., Schwaiger, F. W., Obermeier, A., Stamm, S. The interaction and colocalization of Sam68 with the splicing-associated factor YT521-B in nuclear dots is regulated by the Src family kinase p59(fyn). Molec. Biol. Cell 10: 3909-3926, 1999. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 01/03/2017. 3. Haussmann, I. U., Bodi, Z., Sanchez-Moran, E., Mongan, N. P., Archer, N., Fray, R. G., Soller, M. m(6)A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination. Nature 540: 301-304, 2016.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    YTHDC1 (YTH Domain Containing 1 (YTHDC1))

    别名

    YTHDC1

    背景

    Synonyms: CD160 antigen, Natural killer cell receptor BY55, CD160, BY55

    Tissue Specificity: Expression is restricted to functional NK and cytotoxic T lymphocytes. Expressed in viral-specific effector memory and terminally differentiated effector memory CD8+ T cells. Expressed in memory and activated CD4+ T cell subsets. Expressed at high levels in intraepithelial lymphocytes. Expressed in both alpha-beta and gamma-delta CD8+ T cell subsets. Expressed in umbilical vein endothelial cells. Expressed in monocytes and at lower levels in B cells. Isoform 3: Expressed exclusively in activated NK cells.

    Background: YTH domain-containing protein 1 is a protein that in humans is encoded by the YTHDC1 gene. YTHDC1 is a nuclear protein involved in splice site selection that localises to YT bodies, dynamic subnuclear compartments, which first appear at the beginning of S-phase in the cell cycle and disperse during mitosis.

    分子量

    85 kDa

    基因ID

    91746
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