STK4 抗体 (AA 324-452)
Quick Overview for STK4 抗体 (AA 324-452) (ABIN7601330)
抗原
See all STK4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 324-452
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原理
- Anti-MST1/STK4 Antibody Picoband®
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产品特性
- Anti-MST1/STK4 Antibody Picoband® (ABIN7601330). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MST1/STK4 recombinant protein (Position: E324-D452). Human STK4 shares 93.8% amino acid (aa) sequence identity with mouse STK4.
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anti-serine/threonine Kinase 4 (STK4) (AA 391-485) antibody
STK4 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 4F4 unconjugated
anti-serine/threonine Kinase 4 (STK4) (AA 1-39) antibodySTK4 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D7-8A10 unconjugated
anti-serine/threonine Kinase 4 (STK4) (AA 303-487) antibodySTK4 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 4 (STK4) (C-Term) antibodyKO Validated STK4 适用: 人 WB, IP, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 4 (STK4) (AA 391-485) antibodySTK4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-serine/threonine Kinase 4 (STK4) antibodySTK4 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 4 (STK4) (AA 385-415) antibodySTK4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 4 (STK4) (AA 6-24) antibodySTK4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 4 (STK4) (C-Term) antibodySTK4 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 4 (STK4) (pThr183) antibodySTK4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Abdollahpour, H., Appaswamy, G., Kotlarz, D., Diestelhorst, J., Beier, R., Schaffer, A. A., Gertz, E. M., Schambach, A., Kreipe, H. H., Pfeifer, D., Engelhardt, K. R., Rezaei, N., Grimbacher, B., Lohrmann, S., Sherkat, R., Klein, C. The phenotype of human STK4 deficiency. Blood 119: 3450-3457, 2012. 2. Cheung, W. L., Ajiro, K., Samejima, K., Kloc, M., Cheung, P., Mizzen, C. A., Beeser, A., Etkin, L. D., Chernoff, J., Earnshaw, W. C., Allis, C. D. Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell 113: 507-517, 2003. 3. Creasy, C. L., Chernoff, J. Cloning and characterization of a human protein kinase with homology to Ste20. J. Biol. Chem. 270: 21695-21700, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- STK4 (serine/threonine Kinase 4 (STK4))
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别名
- MST1/STK4
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背景
- Serine/threonine-protein kinase 4 is an enzyme that in humans is encoded by the STK4 gene. The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
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分子量
- 56 kDa
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基因ID
- 6789
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UniProt
- Q13043
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途径
- Tube Formation
抗原
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