Nesprin3 抗体 (AA 322-495)
Quick Overview for Nesprin3 抗体 (AA 322-495) (ABIN7601328)
抗原
See all Nesprin3 (C14orf49) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 322-495
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原理
- Anti-Nesprin3/SYNE3 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-Nesprin3/SYNE3 Antibody Picoband® (ABIN7601328). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Nesprin3/SYNE3 recombinant protein (Position: R322-L495).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gob, E., Schmitt, J., Benavente, R., Alsheimer, M. Mammalian sperm head formation involves different polarization of two novel LINC complexes. PLoS One 5: e12072, 2010. Note: Electronic Article. 2. Wilhelmsen, K., Litjens, S. H. M., Kuikman, I., Tshimbalanga, N., Janssen, H., van den Bout, I., Raymond, K., Sonnenberg, A. Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin. J. Cell Biol. 171: 799-810, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))
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别名
- SYNE3
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背景
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Synonyms: Follicular dendritic cell secreted peptide,FDC secreted protein,FDC-SP,FDCSP,C4orf7,UNQ733/PRO1419,
Tissue Specificity: Abundantly expressed in tonsil, lymph node, and trachea, strong expression in prostate, lower expression in thyroid, stomach, and colon. .
Background: Enables actin filament binding activity and cytoskeleton-nuclear membrane anchor activity. Involved in cytoskeleton organization, establishment of protein localization to membrane, and regulation of cell shape. Located in nuclear membrane. Part of meiotic nuclear membrane microtubule tethering complex. Biomarker of Huntington's disease.
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分子量
- 100 kDa
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基因ID
- 161176
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途径
- Maintenance of Protein Location
抗原
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