Integrin beta 5 抗体 (AA 32-689)
Quick Overview for Integrin beta 5 抗体 (AA 32-689) (ABIN7601320)
抗原
See all Integrin beta 5 (ITGB5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 32-689
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原理
- Anti-Integrin beta 5/ITGB5 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Integrin beta 5/ITGB5 Antibody Picoband® (ABIN7601320). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Integrin beta 5/ITGB5 recombinant protein (Position: S32-D689).
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亚型
- IgG
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anti-Integrin beta 5 (ITGB5) (AA 421-516) antibody
ITGB5 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2C4 unconjugated
anti-Integrin beta 5 (ITGB5) (AA 137-378) antibodyITGB5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 5 (ITGB5) (AA 136-378) antibodyITGB5 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 5 (ITGB5) (C-Term) antibodyITGB5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 5 (ITGB5) (AA 490-720) antibodyITGB5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 5 (ITGB5) (C-Term) antibodyITGB5 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 5 (ITGB5) (AA 421-516) antibodyITGB5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Integrin beta 5 (ITGB5) (C-Term) antibodyITGB5 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 5 (ITGB5) (AA 1-799) antibodyITGB5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 5 (ITGB5) (AA 216-244), (N-Term) antibodyITGB5 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33832 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 4 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Busk, M., Pytela, R., Sheppard, D. Characterization of the integrin alpha-v-beta-6 as a fibronectin-binding protein. J. Biol. Chem. 267: 5790-5796, 1992. 2. McLean, J. W., Vestal, D. J., Cheresh, D. A., Bodary, S. C. cDNA sequence of the human integrin beta 5 subunit. J. Biol. Chem. 265: 17126-17131, 1990. 3. Reynolds, L. E., Wyder, L., Lively, J. C., Taverna, D., Robinson, S. D., Huang, X., Sheppard, D., Hynes, R. O., Hodivala-Dilke, K. M. Enhanced pathological angiogenesis in mice lacking beta-3 integrin or beta-3 and beta-5 integrins. Nature Med. 8: 27-34, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Integrin beta 5 (ITGB5)
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别名
- ITGB5
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背景
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Synonyms: Transforming acidic coiled-coil-containing protein 1,Gastric cancer antigen Ga55,Taxin-1,TACC1,KIAA1103,
Tissue Specificity: Isoform 1, isoform 3 and isoform 5 are ubiquitous. Isoform 2 is strongly expressed in the brain, weakly detectable in lung and colon, and overexpressed in gastric cancer. Isoform 4 is not detected in normal tissues, but strong expression was found in gastric cancer tissues. Down-regulated in a subset of cases of breast cancer. .
Background: This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin.
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分子量
- 90 kDa
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基因ID
- 3693
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UniProt
- P18084
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途径
- Integrin Complex
抗原
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