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Integrin beta 5 抗体 (AA 32-689)

This anti-Integrin beta 5 antibody is a 小鼠 单克隆 antibody detecting Integrin beta 5 in WB, IHC 和 FACS. Suitable for 人.
产品编号 ABIN7601319
发货至: 中国

Quick Overview for Integrin beta 5 抗体 (AA 32-689) (ABIN7601319)

抗原

See all Integrin beta 5 (ITGB5) 抗体
Integrin beta 5 (ITGB5)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Integrin beta 5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

9E2
  • 抗原表位

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    AA 32-689

    原理

    Anti-Integrin beta 5/ITGB5 Antibody Picoband® (monoclonal, 9E2)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Integrin beta 5/ITGB5 Antibody Picoband® (monoclonal, 9E2) (ABIN7601319). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Integrin beta 5/ITGB5 recombinant protein (Position: S32-D689).

    亚型

    IgG1
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Busk, M., Pytela, R., Sheppard, D. Characterization of the integrin alpha-v-beta-6 as a fibronectin-binding protein. J. Biol. Chem. 267: 5790-5796, 1992. 2. McLean, J. W., Vestal, D. J., Cheresh, D. A., Bodary, S. C. cDNA sequence of the human integrin beta 5 subunit. J. Biol. Chem. 265: 17126-17131, 1990. 3. Reynolds, L. E., Wyder, L., Lively, J. C., Taverna, D., Robinson, S. D., Huang, X., Sheppard, D., Hynes, R. O., Hodivala-Dilke, K. M. Enhanced pathological angiogenesis in mice lacking beta-3 integrin or beta-3 and beta-5 integrins. Nature Med. 8: 27-34, 2002.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Integrin beta 5 (ITGB5)

    别名

    ITGB5

    背景

    Synonyms: Heat shock protein 105 kDa, Antigen NY-CO-25, Heat shock 110 kDa protein, HSPH1, HSP105, HSP110, KIAA0201

    Tissue Specificity: Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.

    Background: This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin.

    分子量

    100 kDa

    基因ID

    3693

    UniProt

    P18084

    途径

    Integrin Complex
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