电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Glypican 3 抗体 (AA 32-535)

This anti-Glypican 3 antibody is a 兔 多克隆 antibody detecting Glypican 3 in FACS, WB 和 ELISA. Suitable for 人.
产品编号 ABIN7601314
发货至: 中国

Quick Overview for Glypican 3 抗体 (AA 32-535) (ABIN7601314)

抗原

See all Glypican 3 (GPC3) 抗体
Glypican 3 (GPC3)

适用

  • 184
  • 64
  • 50
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 110
  • 73
  • 5
  • 2
  • 1
  • 1

克隆类型

  • 97
  • 87
  • 5
多克隆

标记

  • 87
  • 15
  • 7
  • 7
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Glypican 3 antibody is un-conjugated

应用范围

  • 96
  • 86
  • 85
  • 69
  • 57
  • 30
  • 26
  • 18
  • 15
  • 15
  • 6
  • 2
  • 2
  • 1
  • 1
Flow Cytometry (FACS), Western Blotting (WB), ELISA
  • 抗原表位

    • 22
    • 16
    • 12
    • 8
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 32-535

    原理

    Anti-Glypican 3/GPC3 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Glypican 3/GPC3 Antibody Picoband® (ABIN7601314). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Glypican 3/GPC3 recombinant protein (Position: D32-A535).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells
    ELISA, 0.1-0.5 μg/mL
    1. Capurro, M. I., Xu, P., Shi, W., Li, F., Jia, A., Filmus, J. Glypican-3 inhibits Hedgehog signaling during development by competing with Patched for Hedgehog binding. Dev. Cell 14: 700-711, 2008. 2. Filmus, J., Capurro, M., Rast, J. Glypicans Genome Biol. 9: 224, 2008. Note: Electronic Article. 3. Filmus, J., Church, J. G., Buick, R. N. Isolation of a cDNA corresponding to a developmentally regulated transcript in rat intestine. Molec. Cell Biol. 8: 4243-4249, 1988.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Glypican 3 (GPC3)

    别名

    GPC3

    背景

    Synonyms: Glypican-3, GTR2-2, Intestinal protein OCI-5, MXR7, Glypican-3 alpha subunit, Glypican-3 beta subunit, GPC3, OCI5

    Tissue Specificity: Highly expressed in lung, liver and kidney.

    Background: Glypican-3 is a protein that, in humans, is encoded by the GPC3 gene. It is mapped to Xq26.2. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

    分子量

    66 kDa

    基因ID

    2719

    UniProt

    P51654

    途径

    Glycosaminoglycan Metabolic Process
You are here:
Chat with us!