PDE8A 抗体 (AA 32-495)
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Quick Overview for PDE8A 抗体 (AA 32-495) (ABIN7601312)
抗原
See all PDE8A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 32-495
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原理
- Anti-PDE8A Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human PDE8A shares 80.5% amino acid (aa) sequence identity with mouse PDE8A.
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产品特性
- Anti-PDE8A Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PDE8A recombinant protein (Position: R32-E495). Human PDE8A shares 80.5% amino acid (aa) sequence identity with mouse PDE8A.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- PDE8A (phosphodiesterase 8A (PDE8A))
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别名
- PDE8A
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背景
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Background: High affinity cAMP-specific and IBMX-insensitive 3', 5'-cyclic phosphodiesterase 8A is an enzyme that in humans is encoded by the PDE8A gene. The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: phosphodiesterase 8A
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分子量
- 93 kDa
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基因ID
- 5151
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UniProt
- O60658
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途径
- cAMP Metabolic Process
抗原
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