PDE8A 抗体 (AA 32-495)
Quick Overview for PDE8A 抗体 (AA 32-495) (ABIN7601312)
抗原
See all PDE8A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 32-495
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原理
- Anti-PDE8A Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-PDE8A Antibody Picoband® (ABIN7601312). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PDE8A recombinant protein (Position: R32-E495). Human PDE8A shares 80.5% amino acid (aa) sequence identity with mouse PDE8A.
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亚型
- IgG
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anti-phosphodiesterase 8A (PDE8A) (AA 32-121) antibody
PDE8A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-phosphodiesterase 8A (PDE8A) (AA 596-829) antibodyPDE8A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) (AA 681-730) antibodyPDE8A 适用: 人, 小鼠, 大鼠, 猴, 兔, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) (AA 551-600) antibodyPDE8A 适用: 人, 大鼠, 猴, 兔, 犬, 马, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) antibodyPDE8A 适用: 人 WB 宿主: 小鼠 Monoclonal EM-52 unconjugated
anti-phosphodiesterase 8A (PDE8A) (AA 1-829) antibodyPDE8A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) (AA 1-120) antibodyPDE8A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) antibodyPDE8A 适用: 人 IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) (C-Term) antibodyPDE8A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) (C-Term) antibodyPDE8A 适用: 人, 小鼠, 大鼠, 兔, 犬, 马, Cow, Pig, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fisher, D. A., Smith, J. F., Pillar, J. S., St. Denis, S. H., Cheng, J. B. Isolation and characterization of PDE8A, a novel human cAMP-specific phosphodiesterase. Biochem. Biophys. Res. Commun. 246: 570-577, 1998. 2. Hetman, J. M., Soderling, S. H., Glavas, N. A., Beavo, J. A. Cloning and characterization of PDE7B, a cAMP-specific phosphodiesterase. Proc. Nat. Acad. Sci. 97: 472-476, 2000. 3. Vasta, V., Shimizu-Albergine, M., Beavo, J. A. Modulation of Leydig cell function by cyclic nucleotide phosphodiesterase 8A. Proc. Nat. Acad. Sci. 103: 19925-19930, 2006. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PDE8A (phosphodiesterase 8A (PDE8A))
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别名
- PDE8A
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: High affinity cAMP-specific and IBMX-insensitive 3', 5'-cyclic phosphodiesterase 8A is an enzyme that in humans is encoded by the PDE8A gene. The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 93 kDa
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基因ID
- 5151
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UniProt
- O60658
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途径
- cAMP Metabolic Process
抗原
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