Anti-SYNJ2BP Antibody Picoband® (ABIN7601295). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
纯化方法
Immunogen affinity purified.
免疫原
E.coli-derived human SYNJ2BP recombinant protein (Position: D32-L145). Human SYNJ2BP shares 88.6% and 86.8% amino acid (aa) sequence identity with mouse and rat SYNJ2BP, respectively.
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL, - 1. Matsuzaki, T., Hanai, S., Kishi, H., Liu, Z., Bao, Y., Kikuchi, A., Tsuchida, K., Sugino, H. Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway. J. Biol. Chem. 277: 19008-19018, 2002. 2. Nemoto, Y., De Camilli, P. Recruitment of an alternatively spliced form of synaptojanin 2 to mitochondria by the interaction with the PDZ domain of a mitochondrial outer membrane protein. EMBO J. 18: 2991-3006, 1999. 3. Stumpf, A. M. Personal Communication. Baltimore, Md. 01/18/2022.
限制
仅限研究用
状态
Lyophilized
溶解方式
Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
抗原
SYNJ2BP
(Synaptojanin 2 Binding Protein (SYNJ2BP))
Synaptojanin-2-binding protein is a protein that in humans is encoded by the SYNJ2BP gene. SYNJ2BP, also known as Synaptojanin 2 Binding Protein, is a protein that interacts with synaptojanin 2, a phosphoinositide phosphatase found in synaptic vesicles. Synaptojanin 2 plays a crucial role in neurotransmitter release and synaptic transmission in neurons, and SYNJ2BP is implicated in regulating these processes through its interaction with synaptojanin 2. The precise molecular and cellular mechanisms of SYNJ2BP are still under investigation, with research focusing on its involvement in neural development, functional abnormalities, and neurologic disorders.