Tpp2 抗体 (AA 32-1001)
Quick Overview for Tpp2 抗体 (AA 32-1001) (ABIN7601293)
抗原
See all Tpp2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 32-1001
-
原理
- Anti-Tripeptidyl peptidase II/TPPII/TPP2 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-Tripeptidyl peptidase II/TPPII/TPP2 Antibody Picoband® (ABIN7601293). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human Tripeptidyl peptidase II/TPPII/TPP2 recombinant protein (Position: E32-K1001).
-
亚型
- IgG
-
-
anti-Tripeptidyl Peptidase II (Tpp2) (AA 1-300) antibody
Tpp2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tripeptidyl Peptidase II (Tpp2) antibodyTpp2 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tripeptidyl Peptidase II (Tpp2) antibodyTpp2 适用: 人, 小鼠, 大鼠 WB, IF, IHC, IC 宿主: 兔 Polyclonal unconjugated
anti-Tripeptidyl Peptidase II (Tpp2) (AA 1-300) antibodyTpp2 适用: 人 IF, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Atallah, I., Quinodoz, M., Campos-Xavier, B., Peter, V. G., Fouriki, A., Bonvin, C., Bottani, A., Kumps, C., Angelini, F., Bellutti Enders, F., Christen-Zaech, S., Rizzi, M., and 11 others. Immune deficiency, autoimmune disease and intellectual disability: a pleiotropic disorder caused by biallelic variants in the TPP2 gene. Clin. Genet. 99: 780-788, 2021. 2. Balow, R.-M., Ragnarsson, U., Zetterqvist, O. Tripeptidyl aminopeptidase in the extralysosomal fraction of rat liver. J. Biol. Chem. 258: 11622-11628, 1983. 3. Bermingham, N. A., McKay, T., Hoyle, J., Hernandez, D., Martin, J. E., Fisher, E. M. C. The gene encoding tripeptidyl peptidase II maps to chromosome 1 in the mouse. Mammalian Genome 7: 390 only, 1996. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- Tpp2 (Tripeptidyl Peptidase II (Tpp2))
-
别名
- TPP2
-
背景
-
Synonyms: Ubiquitin carboxyl-terminal hydrolase 21, Deubiquitinating enzyme 21, Ubiquitin thioesterase 21, Ubiquitin-specific-processing protease 21, USP21, USP23, PP1490
Tissue Specificity: Highly expressed in heart, pancreas and skeletal muscle. Also expressed in brain, placenta, liver and kidney, and at very low level in lung.
Background: Tripeptidyl-peptidase 2 is an enzyme that in humans is encoded by the TPP2 gene. This gene encodes a mammalian peptidase that, at neutral pH , removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase, the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class.
-
分子量
- 138 kDa
-
基因ID
- 7174
-
UniProt
- P29144
抗原
-
