UBR5 抗体 (AA 31-761)
Quick Overview for UBR5 抗体 (AA 31-761) (ABIN7601280)
抗原
See all UBR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-761
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原理
- Anti-UBR5 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-UBR5 Antibody Picoband® (ABIN7601280). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human UBR5 recombinant protein (Position: K31-K761).
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亚型
- IgG
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anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) antibody
UBR5 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (N-Term) antibodyUBR5 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (C-Term) antibodyVerified UBR5 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) antibodyUBR5 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (AA 600-650) antibodyUBR5 适用: 人, 小鼠 WB, IHC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (N-Term) antibodyUBR5 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (N-Term) antibodyUBR5 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (AA 550-760) antibodyUBR5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (N-Term) antibodyUBR5 适用: 人, 小鼠, Cow, 犬, Pig, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (AA 1-50) antibodyUBR5 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Callaghan, M. J., Russell, A. J., Woollatt, E., Sutherland, G. R., Sutherland, R. L., Watts, C. K. W. Identification of a human HECT family protein with homology to the Drosophila tumor suppressor gene hyperplastic discs. Oncogene 17: 3479-3491, 1998. 2. Clancy, J. L., Henderson, M. J., Russell, A. J., Anderson, D. W., Bova, R. J., Campbell, I. G., Choong, D. Y. H., Macdonald, G. A., Mann, G. J., Nolan, T., Brady, G., Olopade, O. I., Woollatt, E., Davies, M. J., Segara, D., Hacker, N. F., Henshall, S. M., Sutherland, R. L., Watts, C. K. W. EDD, the human orthologue of the hyperplastic discs tumour suppressor gene, is amplified and overexpressed in cancer. Oncogene 22: 5070-5081, 2003. 3. Henderson, M. J., Russell, A. J., Hird, S., Munoz, M., Clancy, J. L., Lehrbach, G. M., Calanni, S. T., Jans, D. A., Sutherland, R. L., Watts, C. K. W. EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response. J. Biol. Chem. 277: 26468-26478, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- UBR5 (Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5))
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别名
- UBR5
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背景
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Synonyms: UBR5, EDD, EDD1, HYD, KIAA0896, E3 ubiquitin-protein ligase UBR5, EC 2.3.2.26, E3 ubiquitin-protein ligase, HECT domain-containing 1, HECT-type E3 ubiquitin transferase UBR5, Hyperplastic discs protein homolog, hHYD, Progestin-induced protein
Background: This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.
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分子量
- 309 kDa
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基因ID
- 51366
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UniProt
- O95071
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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