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GLRX3 抗体 (AA 31-307)

This anti-GLRX3 antibody is a 兔 多克隆 antibody detecting GLRX3 in WB, ELISA 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7601262
发货至: 中国

Quick Overview for GLRX3 抗体 (AA 31-307) (ABIN7601262)

抗原

See all GLRX3 抗体
GLRX3 (Glutaredoxin 3 (GLRX3))

适用

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人, 小鼠, 大鼠

宿主

  • 47
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克隆类型

  • 52
  • 5
多克隆

标记

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This GLRX3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 12
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    AA 31-307

    原理

    Anti-GLRX3 Antibody Picoband®

    产品特性

    Anti-GLRX3 Antibody Picoband® (ABIN7601262). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human GLRX3 recombinant protein (Position: K31-V307). Human GLRX3 shares 94.6% and 94.9% amino acid (aa) sequence identity with mouse and rat GLRX3, respectively.
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Hartz, P. A. Personal Communication. Baltimore, Md. 4/22/2009. 2. Haunhorst, P., Hanschmann, E.-M., Brautigam, L., Stehling, O., Hoffmann, B., Muhlenhoff, U., Lill, R., Berndt, C., Lillig, C. H. Crucial function of vertebrate glutaredoxin 3 (PICOT) in iron homeostasis and hemoglobin maturation. Molec. Biol. Cell 24: 1895-1903, 2013. 3. Jeong, D., Kim, J. M., Cha, H., Oh, J. G., Park, J., Yun, S.-H., Ju, E.-S., Jeon, E.-S., Hajjar, R. J., Park, W. J. PICOT attenuates cardiac hypertrophy by disrupting calcineurin-NFAT signaling. Circ. Res. 102: 711-719, 2008.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    GLRX3 (Glutaredoxin 3 (GLRX3))

    别名

    GLRX3

    背景

    Glutaredoxin-3 is a protein that in humans is encoded by the GLRX3 gene. This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene.

    分子量

    40 kDa

    基因ID

    10539

    UniProt

    O76003

    途径

    Cell RedoxHomeostasis
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