SCARA5 抗体 (AA 31-288)
Quick Overview for SCARA5 抗体 (AA 31-288) (ABIN7601260)
抗原
See all SCARA5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-288
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原理
- Anti-SCARA5 Antibody Picoband®
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产品特性
- Anti-SCARA5 Antibody Picoband® (ABIN7601260). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SCARA5 recombinant protein (Position: K31-R288). Human SCARA5 shares 89.9% amino acid (aa) sequence identity with mouse SCARA5.
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anti-Scavenger Receptor Class A, Member 5 (SCARA5) (AA 118-495) antibody
SCARA5 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class A, Member 5 (SCARA5) (AA 303-428) antibodySCARA5 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class A, Member 5 (SCARA5) (C-Term) antibodySCARA5 适用: 人, 小鼠 ELISA, WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class A, Member 5 (SCARA5) (C-Term) antibodySCARA5 适用: 人, 小鼠 ELISA, WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class A, Member 5 (SCARA5) (C-Term) antibodySCARA5 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class A, Member 5 (SCARA5) (AA 392-421), (C-Term) antibodySCARA5 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Huang, J., Zheng, D.-L., Qin, F.-S., Cheng, N., Chen, H., Wan, B.-B., Wang, Y.-P., Xiao, H.-S., Han, Z.-G. Genetic and epigenetic silencing of SCARA5 may contribute to human hepatocellular carcinoma by activating FAK signaling. J. Clin. Invest. 120: 223-241, 2010. 2. Jiang, Y., Oliver, P., Davies, K. E., Platt, N. Identification and characterization of murine SCARA5, a novel class A scavenger receptor that is expressed by populations of epithelial cells. J. Biol. Chem. 281: 11834-11845, 2006. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SCARA5 (Scavenger Receptor Class A, Member 5 (SCARA5))
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别名
- SCARA5
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背景
- Scavenger receptor A5 (SCARA5) is also known as testis expressed scavenger receptor (Tesr). Class A scavenger receptors, including CL-P1, MARCO, SCARA3, and SR-A1, are type II transmembrane proteins that contain a collagenous stalk. Mature human SCARA5 consists of a 60 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 414 aa extracellular domain (ECD) with a spacer, a collagen-like, and a scavenger receptor cysteine-rich (SRCR) domain. Within the ECD, human SCARA5 shares 87 % aa sequence identity with mouse and rat SCARA5. It shares 23 %?34 % aa sequence identity with CL-P1, MARCO, SCARA3, and SR-A1. Alternate splicing generates isoforms that lack the SRCR domain, the transmembrane segment, or the 225 aa spacer region between the membrane and the collagen-like domain. SCARA5 is a cell surface disulfide-linked homotrimer of > 250 kDa. It is highly expressed in testicular Sertoli and germ cells and more weakly in the epithelia of other tissues. During mouse development, SCARA5 expression is attenuated in female embryos at the time of sex determination, whereas it is maintained in the developing testis. SCARA5 is re-expressed in the adult ovary. SCARA5 binds heat-killed bacterial particles but not yeast particles or modified LDL.
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分子量
- 50 kDa
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基因ID
- 286133
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途径
- Transition Metal Ion Homeostasis
抗原
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