SIGLEC12 抗体 (AA 31-287)
Our Local Distributor
北京 101111
Quick Overview for SIGLEC12 抗体 (AA 31-287) (ABIN7601259)
抗原
See all SIGLEC12 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 31-287
-
原理
- Anti-SIGLEC12 Antibody
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-SIGLEC12 Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human SIGLEC12 recombinant protein (Position: S31-H287).
-
亚型
- IgG
-
-
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 503-595) antibody
SIGLEC12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D1 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 27-141) antibodySIGLEC12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) antibodySIGLEC12 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 1-595) antibodySIGLEC12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 20-210) antibodySIGLEC12 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 110-159) antibodySIGLEC12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 38-87) antibodySIGLEC12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 218-267) antibodySIGLEC12 适用: 人, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 20-210) antibodySIGLEC12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (N-Term) antibodySIGLEC12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
-
-
- SIGLEC12 (Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12))
-
别名
- SIGLEC12
-
背景
-
Background: Sialic acid-binding Ig-like lectin 12, or Siglec-XII, is a protein that in humans, is encoded by the SIGLEC12 gene. Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternative splicing results in multiple transcript variants.
Gene Full Name: sialic acid binding Ig like lectin 12
-
分子量
- 70 kDa
-
基因ID
- 89858
-
UniProt
- Q96PQ1
抗原
-
