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MTAP 抗体 (AA 31-283)

This anti-MTAP antibody is a 兔 多克隆 antibody detecting MTAP in WB, ELISA, IF, FACS 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7601258
发货至: 中国

Quick Overview for MTAP 抗体 (AA 31-283) (ABIN7601258)

抗原

See all MTAP 抗体
MTAP (Methylthioadenosine phosphorylase (MTAP))

适用

  • 92
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人, 小鼠, 大鼠

宿主

  • 66
  • 32

克隆类型

  • 50
  • 48
多克隆

标记

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  • 3
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  • 3
  • 2
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  • 1
  • 1
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  • 1
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This MTAP antibody is un-conjugated

应用范围

  • 73
  • 52
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  • 13
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
  • 抗原表位

    • 38
    • 10
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    • 4
    • 4
    • 3
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    • 1
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    AA 31-283

    原理

    Anti-MTAP Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-MTAP Antibody Picoband® (ABIN7601258). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MTAP recombinant protein (Position: E31-H283).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Arnold, W. H. Hereditary bone dysplasia with sarcomatous degeneration. Ann. Intern. Med. 78: 902-906, 1973. 2. Burdon, K. P., Macgregor, S., Hewitt, A. W., Sharma, S., Chidlow, G., Mills, R. A., Danoy, P., Casson, R., Viswanathan, A. C., Liu, J. Z., Landers, J., Henders, A. K., and 13 others. Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1. Nature Genet. 43: 574-578, 2011. 3. Camacho-Vanegas, O., Camacho, S. C., Till, J., Miranda-Lorenzo, I., Terzo, E., Ramirez, M. C., Schramm, V., Cordovano, G., Watts, G., Mehta, S., Kimonis, V., Hoch, B., Philibert, K. D., Raabe, C. A., Bishop, D. F., Glucksman, M. J., Martignetti, J. A. Primate genome gain and loss: a bone dysplasia, muscular dystrophy, and bone cancer syndrome resulting from mutated retroviral-derived MTAP transcripts. Am. J. Hum. Genet. 90: 614-627, 2012.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    MTAP (Methylthioadenosine phosphorylase (MTAP))

    别名

    MTAP

    背景

    Synonyms: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1, COX4I1, COX4

    Tissue Specificity: Ubiquitous.

    Background: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage pathway of both adenine and methionine. The encoded enzyme is deficient in many cancers. Multiple alternatively spliced transcript variants have been described for this gene.

    分子量

    31 kDa

    基因ID

    4507

    UniProt

    Q13126

    途径

    Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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