MTAP 抗体 (AA 31-283)
Quick Overview for MTAP 抗体 (AA 31-283) (ABIN7601258)
抗原
See all MTAP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 31-283
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原理
 - Anti-MTAP Antibody Picoband®
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交叉反应 (详细)
 - No cross-reactivity with other proteins.
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产品特性
 - Anti-MTAP Antibody Picoband® (ABIN7601258). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
 - Immunogen affinity purified.
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免疫原
 - E.coli-derived human MTAP recombinant protein (Position: E31-H283).
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亚型
 - IgG
 
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应用备注
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                        Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Arnold, W. H. Hereditary bone dysplasia with sarcomatous degeneration. Ann. Intern. Med. 78: 902-906, 1973. 2. Burdon, K. P., Macgregor, S., Hewitt, A. W., Sharma, S., Chidlow, G., Mills, R. A., Danoy, P., Casson, R., Viswanathan, A. C., Liu, J. Z., Landers, J., Henders, A. K., and 13 others. Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1. Nature Genet. 43: 574-578, 2011. 3. Camacho-Vanegas, O., Camacho, S. C., Till, J., Miranda-Lorenzo, I., Terzo, E., Ramirez, M. C., Schramm, V., Cordovano, G., Watts, G., Mehta, S., Kimonis, V., Hoch, B., Philibert, K. D., Raabe, C. A., Bishop, D. F., Glucksman, M. J., Martignetti, J. A. Primate genome gain and loss: a bone dysplasia, muscular dystrophy, and bone cancer syndrome resulting from mutated retroviral-derived MTAP transcripts. Am. J. Hum. Genet. 90: 614-627, 2012. - 
                                            
限制
 - 仅限研究用
 
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状态
 - Lyophilized
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溶解方式
 - Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
 - 500 μg/mL
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缓冲液
 - Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
 - 4 °C,-20 °C
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储存方法
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                        At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. 
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- MTAP (Methylthioadenosine phosphorylase (MTAP))
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别名
 - MTAP
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背景
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Synonyms: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1, COX4I1, COX4
Tissue Specificity: Ubiquitous.
Background: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage pathway of both adenine and methionine. The encoded enzyme is deficient in many cancers. Multiple alternatively spliced transcript variants have been described for this gene.
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分子量
 - 31 kDa
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基因ID
 - 4507
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UniProt
 - Q13126
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途径
 - Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
 
抗原
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