CTHRC1 抗体 (AA 31-243)
Quick Overview for CTHRC1 抗体 (AA 31-243) (ABIN7601256)
抗原
See all CTHRC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-243
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原理
- Anti-CTHRC1 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-CTHRC1 Antibody Picoband® (ABIN7601256). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CTHRC1 recombinant protein (Position: S31-K243).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 4 μg/mL, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Orloff, M., Peterson, C., He, X., Ganapathi, S., Heald, B., Yang, Y., Bebek, G., Romigh, T., Song, J. H., Wu, W., David, S., Cheng, Y., Meltzer, S. J., Eng, C. Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett esophagus and esophageal adenocarcinoma. JAMA 306: 410-419, 2011. 2. Pyagay, P., Heroult, M., Wang, Q., Lehnert, W., Belden, J., Liaw, L., Friesel, R. E., Lindner, V. Collagen triple helix repeat containing 1, a novel secreted protein in injured and disease arteries, inhibits collagen expression and promotes cell migration. Circ. Res. 96: 261-268, 2005. 3. Yamamoto, S., Nishimura, O., Misaki, K., Nishita, M., Minami, Y., Yonemura, S., Tarui, H., Sasaki, H. Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex. Dev. Cell 15: 23-36, 2008. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CTHRC1 (Collagen Triple Helix Repeat Containing 1 (CTHRC1))
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别名
- CTHRC1
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背景
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Synonyms: Visual system homeobox 2,Ceh-10 homeodomain-containing homolog,Homeobox protein CHX10,VSX2,CHX10, HOX10,
Tissue Specificity: Abundantly expressed in retinal neuroblasts during eye development and in the inner nuclear layer of the adult retina. Within this layer, expression is stronger in the outer margin where bipolar cells predominate.
Background: This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcript variants have been described. The International Radiation Hybrid Mapping Consortium mapped the CTHRC1 gene to chromosome.
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分子量
- 26 kDa
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基因ID
- 115908
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途径
- Tube Formation
抗原
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