Acetyl-CoA Carboxylase alpha 抗体 (AA 31-2336)
Quick Overview for Acetyl-CoA Carboxylase alpha 抗体 (AA 31-2336) (ABIN7601254)
抗原
See all Acetyl-CoA Carboxylase alpha (ACACA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-2336
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原理
- Anti-ACACA Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ACACA Antibody Picoband® (ABIN7601254). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ACACA recombinant protein (Position: D31-R2336).
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亚型
- IgG
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anti-Acetyl-CoA Carboxylase alpha (ACACA) antibody
ACACA 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) antibodyACACA 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (pSer79) antibodyACACA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (N-Term) antibodyACACA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) antibodyACACA 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (Ser122) antibodyACACA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (pSer80) antibodyACACA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (AA 1-99) antibodyACACA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6H5 unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (AA 78-82) antibodyACACA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Acetyl-CoA Carboxylase alpha (ACACA) (pSer79) antibodyACACA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Abu-Elheiga, L., Brinkley, W. R., Zhong, L., Chirala, S. S., Woldegiorgis, G., Wakil, S. J. The subcellular localization of acetyl-CoA carboxylase 2. Proc. Nat. Acad. Sci. 97: 1444-1449, 2000. 2. Abu-Elheiga, L., Jayakumar, A., Baldini, A., Chirala, S. S., Wakil, S. J. Human acetyl-CoA carboxylase: characterization, molecular cloning, and evidence for two isoforms. Proc. Nat. Acad. Sci. 92: 4011-4015, 1995. 3. Abu-Elheiga, L., Matzuk, M. M., Kordari, P., Oh, W., Shaikenov, T., Gu, Z., Wakil, S. J. Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal. Proc. Nat. Acad. Sci. 102: 12011-12016, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Acetyl-CoA Carboxylase alpha (ACACA)
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别名
- ACACA
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背景
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Synonyms: Serine protease HTRA1, High-temperature requirement A serine peptidase 1, L56, Serine protease 11, HTRA1, HTRA, PRSS11
Tissue Specificity: Widely expressed, with strongest expression in placenta (at protein level). Secreted by synovial fibroblasts. Up- regulated in osteoarthritis and rheumatoid arthritis synovial fluids and cartilage as compared with non-arthritic (at protein level).
Background: Acetyl-CoA carboxylase 1 also known as ACC-alpha or ACCa is an enzyme that in humans is encoded by the ACACA gene. Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
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分子量
- 266 kDa
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基因ID
- 31
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UniProt
- Q13085
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途径
- AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effect
抗原
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