WDR24 抗体 (AA 309-762)
-
- 抗原 See all WDR24 products
- WDR24 (WD Repeat Domain 24 (WDR24))
-
抗原表位
- AA 309-762
- 适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This WDR24 antibody is un-conjugated
-
应用范围
- ELISA, Western Blotting (WB)
- 原理
- Anti-WDR24 Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-WDR24 Antibody Picoband® (ABIN7601246). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human WDR24 recombinant protein (Position: H309-H762).
- 亚型
- IgG
-
anti-WD Repeat Domain 24 (WDR24) (AA 1-298) antibody
WDR24 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Robert, A. , Saxton, Kevin, E. , Knockenhauer, Rachel, L. , & Wolfson, et al. (2016). Structural basis for leucine sensing by the sestrin2-mtorc1 pathway. Science (New York, N.Y.). 2. Wolfson, R. L. , Chantranupong, L. , Saxton, R. A. , Kuang, S. , Scaria, S. M. , & Cantor, J. R. , et al. (2016). [Research Article] Sestrin2 is a leucine sensor for the mTORC1 pathway. 3. Wang, D., Xu, C., Yang, W., Chen, J., Ou, Y., Guan, Y., ... & Liu, Y. (2022). E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression. Molecular Cell, 82(4), 770-784. - 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
- 抗原
- WDR24 (WD Repeat Domain 24 (WDR24))
- 别名
- WDR24 (WDR24 产品)
- 背景
-
Synonyms: Mitochondrial import inner membrane translocase subunit Tim17-A, Inner membrane preprotein translocase Tim17a, TIMM17A, MIMT17, TIM17, TIM17A, TIMM17
Background: WD repeat-containing protein 24 is a protein that in humans is encoded by the WDR24 gene. WDR24 is a component ofthe GATOR2 complex which hasfive known subunits(WDR24, WDR59, Mios, Sec13, and Seh1L). GATOR2 complex positively regulates mTORC1 signaling by acting upstream of orin parallel to GATOR1, which is a GTPase-activating protein (GAP) for RagA or RagB and an inhibitor ofthe amino-acid-sensing pathway.
- 分子量
- 88 kDa
- 基因ID
- 84219
- UniProt
- Q96S15
-
