SHISA7 抗体 (AA 308-535)
Quick Overview for SHISA7 抗体 (AA 308-535) (ABIN7601243)
抗原
See all SHISA7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 308-535
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原理
- Anti-SHISA7 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SHISA7 Antibody Picoband® (ABIN7601243). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SHISA7 recombinant protein (Position: Y308-E535).
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亚型
- IgG
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anti-Shisa Homolog 7 (SHISA7) (AA 308-337) antibody
SHISA7 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB27416 unconjugated
anti-Shisa Homolog 7 (SHISA7) (Middle Region) antibodySHISA7 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Han, W., Li, J., Pelkey, K. A., Pandey, S., Chen, X., Wang, Y.-X., Wu, K., Ge, L., Li, T., Castellano, D., Liu, C., Wu, L.-G., Petralia, R. S., Lynch, J. W., McBain, C. J., Lu, W. Shisa7 is a GABAA receptor auxiliary subunit controlling benzodiazepine actions. Science 366: 246-250, 2019. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 1/30/2017. 3. Pei, J., Grishin, N. V. Unexpected diversity in Shisa-like proteins suggests the importance of their roles as transmembrane adaptors. Cell. Signal. 24: 758-769, 2012. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SHISA7 (Shisa Homolog 7 (SHISA7))
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别名
- SHISA7
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背景
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Synonyms: Placenta-specific protein 9, PLAC9
Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.
Background: Shisa7, a single-passing transmembrane protein, localizes at GABAergic inhibitory synapses and interacts with GABA-A receptors. Shisa7 controlled receptor abundance at synapses and sped up the channel deactivation kinetics. Shisa7 also potently enhanced the action of diazepam, a classic benzodiazepine, on GABA-A receptors. Genetic deletion of Shisa7 selectively impaired GABAergic transmission and diminished the effects of diazepam in mic
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分子量
- 70 kDa
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基因ID
- 729956
抗原
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