Fibulin 1 抗体 (AA 30-703)
Quick Overview for Fibulin 1 抗体 (AA 30-703) (ABIN7601231)
抗原
See all Fibulin 1 (FBLN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-703
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原理
- Anti-Fibulin 1/FBLN1 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-Fibulin 1/FBLN1 Antibody Picoband® (ABIN7601231). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Fibulin 1/FBLN1 recombinant protein (Position: D30-F703).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Argraves, W. S., Dickerson, K., Burgess, W. H., Ruoslahti, E. Fibulin, a novel protein that interacts with the fibronectin receptor-beta subunit cytoplasmic domain. Cell 58: 623-629, 1989. 2. Argraves, W. S., Tran, H., Burgess, W. H., Dickerson, K. Fibulin is an extracellular matrix and plasma glycoprotein with repeated domain structure. J. Cell Biol. 111: 3155-3164, 1990. 3. Bohlega, S., Al-Ajlan, H., Al-Saif, A. Mutation of fibulin-1 causes a novel syndrome involving the central nervous system and connective tissues. Europ. J. Hum. Genet. 22: 640-643, 2014. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Fibulin 1 (FBLN1)
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别名
- FBLN1
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背景
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Synonyms: Insulin gene enhancer protein ISL-1,Islet-1,ISL1,
Tissue Specificity: Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.
Background: FBLN1 is the gene encoding fibulin-1, an extracellular matrix and plasma protein. Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.
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分子量
- 90 kDa
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基因ID
- 2192
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UniProt
- P23142
抗原
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