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GPX4 抗体 (AA 30-197)

This anti-GPX4 antibody is a 小鼠单克隆 antibody detecting GPX4 in WB 和 FACS. Suitable for 人.

产品编号 ABIN7601212

发货至: 中国

Quick Overview for GPX4 抗体 (AA 30-197) (ABIN7601212)

抗原

See all GPX4 抗体

GPX4 (Glutathione Peroxidase 4 (GPX4))

适用

71
56
51
9
4
2
2
2
1
1

人

宿主

小鼠

克隆类型

单克隆

标记

38
5
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This GPX4 antibody is un-conjugated

应用范围

43
27
23
21
10
5
3
2
2
2
1
1
1
1

Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

6I4E7

Discover our top product GPX4 Primary Antibody

抗原表位
11

4

3

2

1

1

1

1

1
AA 30-197

原理

Anti-Glutathione Peroxidase 4/GPX4 Antibody Picoband® (monoclonal, 6I4E7)

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Glutathione Peroxidase 4/GPX4 Antibody Picoband® (monoclonal, 6I4E7) (ABIN7601212). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Glutathione Peroxidase 4/GPX4 recombinant protein (Position: A30-F197).

亚型

IgG2b
anti-Glutathione Peroxidase 4 (GPX4) (AA 30-197) antibody
GPX4 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) (AA 74-197) antibody
GPX4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) (AA 74-197) antibody
GPX4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) (C-Term) antibody
GPX4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) (C-Term) antibody
Verified GPX4 适用: 人 WB, IHC, ELISA, IP 宿主: 山羊 Polyclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) antibody
KO Validated GPX4 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) (AA 74-197) antibody
GPX4 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) (AA 72-121) antibody
GPX4 适用: 人, 小鼠, 大鼠, 斑马鱼, 豚鼠, Cow, 猴, 山羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) (AA 81-93) antibody
GPX4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) antibody
GPX4 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Esworthy RS, Doan K, Doroshow JH, Chu FF (July 1994). "Cloning and sequencing of the cDNA encoding a human testis phospholipid hydroperoxide glutathione peroxidase". Gene 144 (2): 317-8. 2. Smith AC, Mears AJ, Bunker R, Ahmed A, MacKenzie M, Schwartzentruber JA, Beaulieu CL, Ferretti E, Majewski J, Bulman DE, Celik FC, Boycott KM, Graham GE (2014). "Mutations in the enzyme glutathione peroxidase 4 cause Sedaghatian-type spondylometaphyseal dysplasia". Journal of Medical Genetics 51 (7): 470-4.

限制

仅限研究用
状态

Lyophilized

溶解方式

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
抗原

GPX4 (Glutathione Peroxidase 4 (GPX4))

别名

GPX4

背景

Synonyms: Desmin, DES
Background: Glutathione peroxidase 4, also known as GPX4, is an enzyme that in humans is encoded by the GPX4 gene. This gene encodes a member of the glutathione peroxidase protein family. Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. The encoded protein has been identified as a moonlighting protein based on its ability to serve dual functions as a peroxidase as well as a structural protein in mature spermatozoa. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. Alternative splicing results in multiple transcript variants.

分子量

19 kDa

基因ID

2879

UniProt

P36969

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