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STARD3 抗体 (AA 3-429)

This anti-STARD3 antibody is a 兔 多克隆 antibody detecting STARD3 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7601197
发货至: 中国

Quick Overview for STARD3 抗体 (AA 3-429) (ABIN7601197)

抗原

See all STARD3 抗体
STARD3 (StAR-Related Lipid Transfer (START) Domain Containing 3 (STARD3))

适用

人, 小鼠, 大鼠

宿主

  • 6
  • 2

克隆类型

  • 7
  • 1
多克隆

标记

  • 8
This STARD3 antibody is un-conjugated

应用范围

  • 7
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 3
    • 2
    • 1
    AA 3-429

    原理

    Anti-MLN64/STARD3 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-MLN64/STARD3 Antibody Picoband® (ABIN7601197). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MLN64/STARD3 recombinant protein (Position: K3-E429).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Akiyama, N., Sasaki, H., Ishizuka, T., Kishi, T., Sakamoto, H., Onda, M., Hirai, H., Yazaki, Y., Sugimura, T., Terada, M. Isolation of a candidate gene, CAB1, for cholesterol transport to mitochondria from the c-ERBB-2 amplicon by a modified cDNA selection method. Cancer Res. 57: 3548-3553, 1997. 2. Alpy, F., Boulay, A., Moog-Lutz, C., Andarawewa, K. L., Degot, S., Stoll, I., Rio, M.-C., Tomasetto, C. Metastatic lymph node 64 (MLN64), a gene overexpressed in breast cancers, is regulated by Sp/KLF transcription factors. Oncogene 22: 3770-3780, 2003. 3. Alpy, F., Stoeckel, M.-E., Dierich, A., Escola, J.-M., Wendling, C., Chenard, M.-P., Vanier, M. T., Gruenberg, J., Tomasetto, C., Rio, M.-C. The steroidogenic acute regulatory protein homolog MLN64, a late endosomal cholesterol-binding protein. J. Biol. Chem. 276: 4261-4269, 2001.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    STARD3 (StAR-Related Lipid Transfer (START) Domain Containing 3 (STARD3))

    别名

    STARD3

    背景

    Synonyms: Cytoskeleton-associated protein 5, Colonic and hepatic tumor overexpressed gene protein, Ch-TOG, CKAP5, KIAA0097

    Tissue Specificity: Expressed in fetal brain. Highly expressed in brain and placenta. Lower levels in heart, liver, thymus, kidney and lung. Located to endothelial cells and neuronal cells of the suprachiasmatic nucleus (SCN). Also detected in endothelial cells of the heart, lung and kidney. In the brain, specifically expressed in the thalamus, hippocampus and amygdala.

    Background: StAR related lipid transfer domain containing 3 (STARD3) is a protein that in humans is encoded by the STARD3 gene. This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants.

    分子量

    51 kDa

    基因ID

    10948

    UniProt

    Q14849

    途径

    C21-Steroid Hormone Metabolic Process
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