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CNOT7 抗体 (AA 3-285)

This anti-CNOT7 antibody is a 兔 多克隆 antibody detecting CNOT7 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7601184
发货至: 中国

Quick Overview for CNOT7 抗体 (AA 3-285) (ABIN7601184)

抗原

See all CNOT7 抗体
CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

适用

  • 36
  • 19
  • 7
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 32
  • 4

克隆类型

  • 33
  • 3
多克隆

标记

  • 24
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CNOT7 antibody is un-conjugated

应用范围

  • 27
  • 21
  • 14
  • 11
  • 7
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-285

    原理

    Anti-CNOT7 Antibody Picoband®

    产品特性

    Anti-CNOT7 Antibody Picoband® (ABIN7601184). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CNOT7 recombinant protein (Position: A3-S285).
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Albert, T. K., Lemaire, M., van Berkum, N. L., Gentz, R., Collart, M. A., Timmers, H. T. M. Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits. Nucleic Acids Res. 28: 809-817, 2000. 2. Draper, M. P., Salvadore, C., Denis, C. L. Identification of a mouse protein whose homolog in Saccharomyces cerevisiae is a component of the CCR4 transcriptional regulatory complex. Molec. Cell. Biol. 15: 3487-3495, 1995. 3. Nakamura, T., Yao, R., Ogawa, T., Suzuki, T., Ito, C., Tsunekawa, N., Inoue, K., Ajima, R., Miyasaka, T., Yoshida, Y., Ogura, A., Toshimori, K., Noce, T., Yamamoto, T., Noda, T. Oligo-astheno-teratozoospermia in mice lacking Cnot7, a regulator of retinoid X receptor beta. Nature Genet. 36: 528-533, 2004.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

    别名

    CNOT7

    背景

    CCR4-NOT transcription complex subunit 7 is a protein that in humans is encoded by the CNOT7 gene. The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.

    分子量

    33 kDa

    基因ID

    29883

    途径

    Ribonucleoprotein Complex Subunit Organization
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