电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

BCR 抗体 (AA 3-264)

This anti-BCR antibody is a 兔 多克隆 antibody detecting BCR in WB, ELISA 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7601180
发货至: 中国

Quick Overview for BCR 抗体 (AA 3-264) (ABIN7601180)

抗原

See all BCR 抗体
BCR (Breakpoint Cluster Region (BCR))

适用

  • 98
  • 55
  • 25
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 93
  • 4
  • 4

克隆类型

  • 96
  • 5
多克隆

标记

  • 61
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BCR antibody is un-conjugated

应用范围

  • 72
  • 37
  • 33
  • 27
  • 26
  • 26
  • 19
  • 15
  • 14
  • 11
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 30
    • 16
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-264

    原理

    Anti-BCR Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-BCR Antibody Picoband® (ABIN7601180). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human BCR recombinant protein (Position: D3-N264).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. "Entrez Gene: Breakpoint cluster region". 2. Puil L, Liu J, Gish G, Mbamalu G, Bowtell D, Pelicci PG, Arlinghaus R, Pawson T (February 1994). "Bcr-Abl oncoproteins bind ly to activators of the Ras signalling pathway". EMBO J. 13 (4): 764-73. 3. Pendergast AM, Muller AJ, Havlik MH, Maru Y, Witte ON (July 1991). "BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner".Cell 66 (1): 161-71.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    BCR (Breakpoint Cluster Region (BCR))

    别名

    BCR

    背景

    Synonyms: Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF, IL10

    Tissue Specificity: Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.

    Background: The breakpoint cluster region protein (BCR) is a protein that in humans is encoded by the BCR gene. A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    160 kDa

    基因ID

    613

    UniProt

    P11274

    途径

    Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
You are here:
Chat with us!