TNNI2 抗体 (AA 3-182)
Quick Overview for TNNI2 抗体 (AA 3-182) (ABIN7601172)
抗原
See all TNNI2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3-182
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原理
- Anti-Troponin I fast skeletal muscle/TNNI2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Troponin I fast skeletal muscle/TNNI2 Antibody Picoband® (ABIN7601172). Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Troponin I fast skeletal muscle/TNNI2 recombinant protein (Position: D3-S182).
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亚型
- IgG
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anti-Fast Skeletal Troponin I (TNNI2) antibody
TNNI2 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2F12A11 unconjugated
anti-Fast Skeletal Troponin I (TNNI2) antibodyTNNI2 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2F12G2 unconjugated
anti-Fast Skeletal Troponin I (TNNI2) (AA 1-182) antibodyTNNI2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fast Skeletal Troponin I (TNNI2) (AA 1-100) antibodyTNNI2 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Fast Skeletal Troponin I (TNNI2) antibodyTNNI2 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fast Skeletal Troponin I (TNNI2) antibodyTNNI2 适用: 人 WB, FACS, IF, EIA 宿主: 小鼠 Monoclonal 2F12G2 unconjugated
anti-Fast Skeletal Troponin I (TNNI2) (AA 2-100) antibodyTNNI2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D5 unconjugated
anti-Fast Skeletal Troponin I (TNNI2) (AA 1-182) antibodyTNNI2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fast Skeletal Troponin I (TNNI2) antibodyTNNI2 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 11E6 unconjugated
anti-Fast Skeletal Troponin I (TNNI2) antibodyTNNI2 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunofluorescence, 5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Barton, P. J. R., Townsend, P. J., Brand, N. J., Yacoub, M. H. Localization of the fast skeletal muscle troponin I gene (TNNI2) to 11p15.5: genes for troponin I and T are organized in pairs. Ann. Hum. Genet. 61: 519-523, 1997. 2. Drera, B., Zoppi, N., Barlati, S., Colombi, M. Recurrence of the p.R156X TNNI2 mutation in distal arthrogryposis type 2B. (Letter) Clin. Genet. 70: 532-534, 2006. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- TNNI2 (Fast Skeletal Troponin I (TNNI2))
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别名
- TNNI2
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背景
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Synonyms: Troponin I, fast skeletal muscle, Troponin I, fast-twitch isoform, TNNI2
Tissue Specificity: Highly expressed in brain and weakly in heart, small intestine and uterus. Isoform 1A is mostly expressed in granular cell and molecular layer. Isoform 1B is mostly expressed in Purkinje cells. Isoform 1E is predominantly expressed in peripheral tissues as kidney, lung, trachea, colon, small intestine, stomach, bone marrow, thymus and mammary gland. .
Background: Troponin I, fast skeletal muscle is a protein that in humans is encoded by the TNNI2 gene. It is mapped to 11p15.5. This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.
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分子量
- 24 kDa
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基因ID
- 7136
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UniProt
- P48788
抗原
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