Dynamin 3 抗体 (AA 295-712)
Quick Overview for Dynamin 3 抗体 (AA 295-712) (ABIN7601163)
抗原
See all Dynamin 3 (DNM3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 295-712
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原理
- Anti-Dynamin 3/DNM3 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Dynamin 3/DNM3 Antibody Picoband® (ABIN7601163). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DNM3 recombinant protein (Position: N295-N712).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Gray, N. W., Fourgeaud, L., Huang, B., Chen, J., Cao, H., Oswald, B. J., Hemar, A., McNiven, M. A. Dynamin 3 is a component of the postsynapse, where it interacts with mGluR5 and Homer. Curr. Biol. 13: 510-515, 2003. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 7/2/2012. 3. Lu, J., Helton, T. D., Blanpied, T. A., Racz, B., Newpher, T. M., Weinberg, R. J., Ehlers, M. D. Postsynaptic positioning of endocytic zones and AMPA receptor cycling by physical coupling of dynamin-3 to Homer. Neuron 55: 874-889, 2007. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Dynamin 3 (DNM3)
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别名
- DNM3
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背景
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Synonyms: Disintegrin and metalloproteinase domain-containing protein 28,ADAM 28,3.4.24.-,Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II,eMDC II,Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L,MDC-L,ADAM28,ADAM23, MDCL,
Tissue Specificity: Expressed predominantly in secondary lymphoid tissues, such as lymph node, spleen, small intestine, stomach, colon, appendix and trachea. The lymphocyte population is responsible for expression of this protein in these tissues. Isoform 2 is expressed preferentially in spleen.
Background: Dynamin-3 is a protein that in humans is encoded by the DNM3 gene. This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants.
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分子量
- 110 kDa
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基因ID
- 26052
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途径
- Toll-Like Receptors Cascades
抗原
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