Neurexin 3 抗体 (AA 294-549)
Quick Overview for Neurexin 3 抗体 (AA 294-549) (ABIN7601160)
抗原
See all Neurexin 3 (NRXN3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 294-549
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原理
- Anti-NRXN3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-NRXN3 Antibody Picoband® (ABIN7601160). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NRXN3 recombinant protein (Position: R294-P549).
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亚型
- IgG
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anti-Neurexin 3 (NRXN3) (AA 1584-1643) antibody
NRXN3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurexin 3 (NRXN3) (N-Term) antibodyNRXN3 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neurexin 3 (NRXN3) (Internal Region) antibodyNRXN3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurexin 3 (NRXN3) (AA 201-432) antibodyNRXN3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neurexin 3 (NRXN3) (AA 373-432) antibodyNRXN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Neurexin 3 (NRXN3) (AA 1298-1494) antibodyNRXN3 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Neurexin 3 (NRXN3) (AA 39-52), (Extracellular) antibodyNRXN3 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hishimoto, A., Liu, Q.-R., Drgon, T., Pletnikova, O., Walther, D., Zhu, X.-G., Troncoso, J. C., Uhl, G. R. Neurexin 3 polymorphisms are associated with alcohol dependence and altered expression of specific isoforms. Hum. Molec. Genet. 16: 2880-2891, 2007. 2. Keum, S., Kim, A., Shin, J. J., Kim, J.-H., Park, J., Shin, H.-S. A missense variant at the Nrxn3 locus enhances empathy fear in the mouse. Neuron 98: 588-601, 2018. 3. Missler, M., Sudhof, T. C. Neurexins: three genes and 1001 products. Trends Genet. 14: 20-26, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Neurexin 3 (NRXN3)
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别名
- NRXN3
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背景
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Synonyms: Protein phosphatase 1 regulatory subunit 14A,17 kDa PKC-potentiated inhibitory protein of PP1,Protein kinase C-potentiated inhibitor protein of 17 kDa,CPI-17,PPP1R14A,CPI17, PPP1INL,
Tissue Specificity: Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta. .
Background: Neurexin-3-alpha is a protein that in humans is encoded by the NRXN3 gene. This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder.
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分子量
- 185 kDa
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基因ID
- 9369
抗原
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