RFXANK 抗体 (AA 29-260)
Quick Overview for RFXANK 抗体 (AA 29-260) (ABIN7601120)
抗原
See all RFXANK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 29-260
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原理
- Anti-RFXANK Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-RFXANK Antibody Picoband® (ABIN7600269). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RFXANK recombinant protein (Position: E29-E260). Human RFXANK shares 85.1% amino acid (aa) sequence identity with mouse RFXANK.
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亚型
- IgG
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anti-Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK) antibody
RFXANK 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2G7 unconjugated
anti-Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK) (AA 1-90) antibodyRFXANK 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G10 unconjugated
anti-Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK) (AA 3-84) antibodyRFXANK 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK) antibodyRFXANK 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 3B4 unconjugated
anti-Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK) (AA 1-237) antibodyRFXANK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK) (AA 1-237) antibodyRFXANK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Lennon-Dumenil, A.-M., Barbouche, M.-R., Vedrenne, J., Prod'Homme, T., Bejaoui, M., Ghariani, S., Charron, D., Fellous, M., Dellagi, K., Alcaide-Loridan, C. Uncoordinated HLA-D gene expression in a RFXANK-defective patient with MHC class II deficiency. J. Immun. 166: 5681-5687, 2001. 2. Lin, J. H., Makris, A., McMahon, C., Bear, S. E., Patriotis, C., Prasad, V. R., Brent, R., Golemis, E. A., Tsichlis, P. N. The ankyrin repeat-containing adaptor protein Tvl-1 is a novel substrate and regulator of Raf-1. J. Biol. Chem. 274: 14706-14715, 1999. 3. Lisowska-Grospierre, B., Fondaneche, M. C., Rols, M. P., Griscelli, C., Fischer, A. Two complementation groups account for most cases of inherited MHC class II deficiency. Hum. Molec. Genet. 3: 953-958, 1994. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))
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别名
- RFXANK
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: DNA-binding protein RFXANK is a protein that in humans is encoded by the RFXANK gene. Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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分子量
- 34 kDa
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基因ID
- 8625
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UniProt
- O14593
抗原
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