ADGRE5 (AA 287-816) 抗体
Quick Overview for ADGRE5 (AA 287-816) 抗体 (ABIN7601103)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 287-816
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原理
- Anti-CD97/Adgre5 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CD97/Adgre5 Antibody Picoband® (ABIN7601103). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse CD97/Adgre5 recombinant protein (Position: Q287-S816).
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亚型
- IgG
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anti-ADGRE5 (C-Term) antibody
Verified 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-ADGRE5 (AA 240-435) antibody适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-ADGRE5 (AA 499-512), (Extracellular) antibody适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Hamann, J., Eichler, W., Hamann, D., Kerstens, H. M. J., Poddighe, P. J., Hoovers, J. M. N., Hartmann, E., Strauss, M., van Lier, R. A. W. Expression cloning and chromosomal mapping of the leukocyte activation antigen CD97, a new seven-span transmembrane molecule of the secretin receptor superfamily with an unusual extracellular domain. J. Immun. 155: 1942-1950, 1995. 2. Hamann, J., Hartmann, E., van Lier, R. A. W. Structure of the human CD97 gene: exon shuffling has generated a new type of seven-span transmembrane molecule related to the secretin receptor superfamily. Genomics 32: 144-147, 1996. 3. Hamann, J., Vogel, B., van Schijndel, G. M., van Lier, R. A. The seven-span transmembrane receptor CD97 has a cellular ligand (CD55, DAF). J. Exp. Med. 184: 1185-1189, 1996. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ADGRE5
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背景
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Synonyms: C-C motif chemokine 6, Protein C10, Small-inducible cytokine A6, CCL6 (22-95), CCL6 (23-95), Ccl6, C10, Scya6
Tissue Specificity: Expressed in myelopoietic bone marrow cultures stimulated by GM-CSF.
Background: Cluster of differentiation 97 is a protein also known as BL-Ac[F2] encoded by the ADGRE5 gene. This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.
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分子量
- 92 kDa
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基因ID
- 26364
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UniProt
- Q9Z0M6
抗原
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