ITGA2 抗体 (AA 285-1181)
Quick Overview for ITGA2 抗体 (AA 285-1181) (ABIN7601097)
抗原
See all ITGA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 285-1181
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原理
- Anti-Integrin alpha 2/ITGA2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Integrin alpha 2/ITGA2 Antibody Picoband® (ABIN7601097). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Integrin alpha 2/ITGA2 recombinant protein (Position: E285-S1181).
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亚型
- IgG
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anti-Integrin alpha 2 (ITGA2) (AA 30-119) antibody
ITGA2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-Integrin alpha 2 (ITGA2) (AA 994-1132) antibodyITGA2 适用: 人 FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 5E3A8 unconjugated
anti-Integrin alpha 2 (ITGA2) antibodyITGA2 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Integrin alpha 2 (ITGA2) (AA 170-361) antibodyITGA2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha 2 (ITGA2) (Internal Region) antibodyITGA2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha 2 (ITGA2) (C-Term) antibodyITGA2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha 2 (ITGA2) (AA 74-277) antibodyITGA2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha 2 (ITGA2) (AA 678-894) antibodyITGA2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha 2 (ITGA2) (AA 188-365) antibodyITGA2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha 2 (ITGA2) antibodyITGA2 适用: 人, Baboon, Cynomolgus, 猕猴 FACS, IHC (fro), Func 宿主: 小鼠 Monoclonal AK7 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bettaieb, A., Fromont, P., Rodet, M., Godeau, B., Duedari, N., Bierling, P. Br(b), a platelet alloantigen involved in neonatal alloimmune thrombocytopenia. Vox Sang. 60: 230-234, 1991. 2. Carlsson, L. E., Santoso, S., Spitzer, C., Kessler, C., Greinacher, A. The alpha-2 gene coding sequence T807/A873 of the platelet collagen receptor integrin alpha-2/beta-1 might be a genetic risk factor for the development of stroke in younger patients. Blood 93: 3583-3586, 1999. 3. Fan, X., Moltedo, B., Mendoza, A., Davydov, A. N., Faire, M. B., Mazutis, L., Sharma, R., Pe'er, D., Chudakov, D. M., Rudensky, A. Y. CD49b defines functionally mature Treg cells that survey skin and vascular tissues. J. Exp. Med. 215: 2796-2814, 2018. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ITGA2 (Integrin alpha 2 (ITGA2))
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别名
- ITGA2
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背景
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Synonyms: Mitochondrial fission 1 protein, FIS1 homolog, hFis1, Tetratricopeptide repeat protein 11, TPR repeat protein 11, FIS1, TTC11, CGI-135
Tissue Specificity: Ubiquitous. Expressed in the rod and cone photoreceptors, extending from the tips of the outer segment (OS) through the inner segment (IS) and outer nuclear layer (ONL) and into the synaptic terminals of the outer plexiform layer (ONL). Also detected in the bipolar, horizontal and amacrine cells in the inner nuclear layer (INL), extending to the inner plexiform layer (IPL) and though the ganglion cell layer (GCL) and into the nerve fiber layer (NFL) (at protein level).
Background: Integrin alpha-2, or CD49b (cluster of differentiation 49b), is a protein which in humans is encoded by the CD49b gene. This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
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分子量
- 165 kDa
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基因ID
- 3673
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UniProt
- P17301
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途径
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
抗原
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