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BCL6 抗体 (AA 28-336)

Name: BCL6 抗体 (AA 28-336)
SKU: ABIN7601073
Availability: OutOfStock

This anti-BCL6 antibody is a 兔多克隆 antibody detecting BCL6 in WB, FACS 和 ELISA. Suitable for 人.

产品编号 ABIN7601073

发货至: 中国

Quick Overview for BCL6 抗体 (AA 28-336) (ABIN7601073)

抗原

See all BCL6 抗体

BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

适用

人

宿主

兔

克隆类型

多克隆

标记

This BCL6 antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), ELISA

Discover our top product BCL6 Primary Antibody

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AA 28-336

原理

Anti-BCL6 Antibody Picoband®

产品特性

Anti-BCL6 Antibody Picoband® (ABIN7601073). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human BCL6 recombinant protein (Position: R28-K336). Human BCL6 shares 90.6% amino acid (aa) sequence identity with mouse BCL6.
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 501-600) antibody
BCL6 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IHC (fro), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 6 (BCL6) (Internal Region) antibody
BCL6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 256-389) antibody
BCL6 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal BCL6-1527 unconjugated

anti-B-Cell CLL/lymphoma 6 (BCL6) (Internal Region) antibody
BCL6 适用: 人, 小鼠 WB, IHC (p), IP, ChIP 宿主: 兔 Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 147-276) antibody
BCL6 适用: 人 FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 2G1B6 unconjugated

anti-B-Cell CLL/lymphoma 6 (BCL6) (Internal Region) antibody
BCL6 适用: 人, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 519-547) antibody
BCL6 适用: 人, 小鼠 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 256-389) antibody
BCL6 适用: 人 WB 宿主: 小鼠 Monoclonal BCL6-1475 unconjugated

anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 256-389) antibody
BCL6 适用: 人 IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal BCL6-1982 unconjugated

anti-B-Cell CLL/lymphoma 6 (BCL6) (pSer333) antibody
BCL6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Akasaka, T., Miura, I., Takahashi, N., Akasaka, H., Yonetani, N., Ohno, H., Fukuhara, S., Okuma, M. A recurring translocation, t(3,6)(q27,p21), in non-Hodgkin's lymphoma results in replacement of the 5-prime regulatory region of BCL6 with a novel H4 histone gene. Cancer Res. 57: 7-12, 1997. 2. Barnett, B. E., Ciocca, M. L., Goenka, R., Barnett, L. G., Wu, J., Laufer, T. M., Burkhardt, J. K., Cancro, M. P., Reiner, S. L. Asymmetric B cell division in the germinal center reaction. Science 335: 342-344, 2012. 3. Baron, B. W., Nucifora, G., McCabe, N., Espinosa, R., III, Le Beau, M. M., McKeithan, T. W. Identification of the gene associated with the recurring chromosomal translocations t(3,14)(q27,q32) and t(3,22)(q27,q11) in B-cell lymphomas. Proc. Nat. Acad. Sci. 90: 5262-5266, 1993.

限制

仅限研究用
状态

Lyophilized

溶解方式

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
抗原

BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

别名

BCL6

背景

Bcl-6 (B-cell lymphoma 6) is a protein that in humans is encoded by the BCL6 gene. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

分子量

88 kDa

基因ID

604

UniProt

P41182

途径

Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus