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FAM59A 抗体 (AA 277-753)

This anti-FAM59A antibody is a 兔 多克隆 antibody detecting FAM59A in ELISA, WB, IHC 和 FACS. Suitable for 人.
产品编号 ABIN7601055
发货至: 中国

Quick Overview for FAM59A 抗体 (AA 277-753) (ABIN7601055)

抗原

See all FAM59A 抗体
FAM59A (Family with Sequence Similarity 59, Member A (FAM59A))

适用

  • 22
  • 2
  • 2

宿主

  • 22

克隆类型

  • 22
多克隆

标记

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This FAM59A antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 5
    • 2
    • 1
    AA 277-753

    原理

    Anti-GAREM1 Antibody Picoband®

    产品特性

    Anti-GAREM1 Antibody Picoband® (ABIN7601055). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human GAREM1 recombinant protein (Position: Q277-E753). Human GAREM1 shares 86.8% amino acid (aa) sequence identity with mouse GAREM1.
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry, 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Nishino, T., Matsunaga, R., Konishi, H. Functional relationship between CABIT, SAM and 14-3-3 binding domains of GAREM1 that play a role in its subcellular localization. Biochem. Biophys. Res. Commun. 464: 616-621, 2015. 2. Taniguchi, T., Tanaka, S., Ishii, A., Watanabe, M., Fujitani, N., Sugeo, A., Gotoh, S., Ohta, T., Hiyoshi, M., Matsuzaki, H., Sakai, N., Konishi, H. A brain-specific Grb2-associated regulator of extracellular signal-regulated kinase (Erk)mitogen-activated protein kinase (MAPK) (GAREM) subtype, GAREM2, contributes to neurite outgrowth of neuroblastoma cells by regulating Erk signaling. J. Biol. Chem. 288: 29934-29942, 2013. 3. Tashiro, K., Tsunematsu, T., Okubo, H., Ohta, T., Sano, E., Yamauchi, E., Taniguchi, H., Konishi, H. GAREM, a novel adaptor protein for growth factor receptor-bound protein 2, contributes to cellular transformation through activation of extracellular signal-regulated kinase signaling. J. Biol. Chem. 284: 20206-20214, 2009.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    FAM59A (Family with Sequence Similarity 59, Member A (FAM59A))

    别名

    GAREM1

    背景

    This gene encodes an adaptor protein which functions in the epidermal growth factor (EGF) receptor-mediated signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    97 kDa

    基因ID

    64762

    UniProt

    Q9H706

    途径

    EGFR Signaling Pathway
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