ACCN1 抗体 (AA 27-512)
Quick Overview for ACCN1 抗体 (AA 27-512) (ABIN7601023)
抗原
See all ACCN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-512
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原理
- Anti-ACCN1/ASIC2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ACCN1/ASIC2 Antibody Picoband® (ABIN7601023). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ACCN1/ASIC2 recombinant protein (Position: H27-C512).
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亚型
- IgG
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anti-Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (AA 197-345) antibody
ACCN1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (AA 481-530) antibodyACCN1 适用: 人, 马, 兔, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (AA 120-148) antibodyACCN1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22513 unconjugated
anti-Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (AA 127-156), (Middle Region) antibodyACCN1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (C-Term) antibodyACCN1 适用: 人, 大鼠, 小鼠, 马, 兔, Cow, 斑马鱼, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (AA 120-400) antibodyACCN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) antibodyACCN1 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (AA 120-148) antibodyACCN1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (AA 2-18), (Intracellular) antibodyKO Validated ACCN1 适用: 人 WB, IHC, IF, IC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Garcia-Anoveros, J., Derfler, B., Neville-Golden, J., Hyman, B. T., Corey, D. P. BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels. Proc. Nat. Acad. Sci. 94: 1459-1464, 1997. 2. Jahr, H., van Driel, M., van Osch, G. J. V. M., Weinans, H., van Leeuwen, J. P. T. M. Identification of acid-sensing ion channels in bone. Biochem. Biophys. Res. Commun. 337: 349-354, 2005. 3. Lu, Y., Ma, X., Sabharwal, R., Snitsarev, V., Morgan, D., Rahmouni, K., Drummond, H. A., Whiteis, C. A., Costa, V., Price, M., Benson, C., Welsh, M. J., Chapleau, M. W., Abboud, F. M. The ion channel ASIC2 is required for baroreceptor and autonomic control of the circulation. Neuron 64: 885-897, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))
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别名
- ASIC2
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背景
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Synonyms: Acid-sensing ion channel 2, ASIC2, Amiloride-sensitive brain sodium channel, Amiloride-sensitive cation channel 1, neuronal, Amiloride-sensitive cation channel neuronal 1, Brain sodium channel 1, BNC1, BNaC1, Mammalian degenerin homolog, MDEG, ASIC2, ACCN, ACCN1, BNAC1, MDEG
Tissue Specificity: Brain and spinal cord. Isoform 1 is also detected in testis, liver, colon and ovary.
Background: Amiloride-sensitive cation channel 1, neuronal, also known as ASIC2,?is a?protein?that in?humans?is encoded by the?ACCN1 gene. This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.?
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分子量
- 58 kDa
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基因ID
- 40
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UniProt
- Q16515
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途径
- Sensory Perception of Sound
抗原
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