CASK 抗体 (AA 27-498)
Quick Overview for CASK 抗体 (AA 27-498) (ABIN7601021)
抗原
See all CASK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-498
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原理
- Anti-CASK Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CASK Antibody Picoband® (ABIN7601021). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CASK recombinant protein (Position: R27-D498).
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亚型
- IgG
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anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (AA 1-300) antibody
CASK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (AA 262-291) antibodyCASK 适用: 人 WB 宿主: 兔 Polyclonal RB15769 unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (AA 470-760) antibodyCASK 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) antibodyCASK 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (N-Term) antibodyCASK 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (AA 651-750) antibodyCASK 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (AA 564-596), (C-Term) antibodyCASK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1248 unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (AA 589-616) antibodyCASK 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) antibodyCASK 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (AA 1-337), (AA 318-415) antibodyCASK 适用: 小鼠, 大鼠, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Atasoy, D., Schoch, S., Ho, A., Nadasy, K. A., Liu, X., Zhang, W., Mukherjee, K., Nosyreva, E. D., Fernandez-Chacon, R., Missler, M., Kavalali, E. T., Sudhof, T. C. Deletion of CASK in mice is lethal and impairs synaptic function. Proc. Nat. Acad. Sci. 104: 2525-2530, 2007. 2. Butz, S., Okamoto, M., Sudhof, T. C. A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Cell 94: 773-782, 1998. 3. Cohen, A. R., Woods, D. F., Marfatia, S. M., Walther, Z., Chishti, A. H., Anderson, J. M. Human CASK/LIN-2 binds syndecan-2 and protein 4.1 and localizes to the basolateral membrane of epithelial cells. J. Cell Biol. 142: 129-138, 1998. Note: Erratum: J. Cell Biol. 142: following 1156, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))
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别名
- CASK
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背景
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Synonyms: Probable ATP-dependent RNA helicase DDX4, DEAD box protein 4, Vasa homolog, DDX4, VASA
Tissue Specificity: Expressed only in ovary and testis. Expressed in migratory primordial germ cells in the region of the gonadal ridge in both sexes.
Background: Peripheral plasma membrane protein CASK is a protein that in humans is encoded by the CASK gene. This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, intellectual disability and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked intellectual disability. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 120 kDa
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基因ID
- 8573
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UniProt
- O14936
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途径
- Synaptic Vesicle Exocytosis
抗原
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